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Posaconazole
INFORMATION ABOUT POSACONAZOLE
Posaconazole Uses
Posaconazole is used in the treatment of severe fungal infections.
How Posaconazole works
Posaconazole is an antifungal that works by inhibiting the enzyme essential for the synthesis of ergosterol, a key component of fungal cell membranes. It disrupts the production of ergosterol, damaging the fungal cell membrane, leading to cell death. This action makes it effective in preventing and treating invasive Aspergillus and Candida infections in immunocompromised patients, as well as treating oropharyngeal candidiasis, including cases resistant to other azoles like itraconazole or fluconazole.
Common side effects of Posaconazole
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Fever, Decreased potassium level in blood, Nausea, Diarrhea, Cough, Vomiting, Headache
CONTENT DETAILS
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Written By
Dr. Anuj Saini
MMST, MBBS
Reviewed By
Dr. Rajeev Sharma
MBA, MBBS
Last updated
21 Jul 2025 | 09:16 AM (UTC)
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Medicine brands for Posaconazole
Expert advice for Posaconazole
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Take Posaconazole with food to enhance the absorption, preferably at the same time every day.
- Do not take indigestion remedies (antacids) within two hours of taking Posaconazole.
- Your doctor may check your liver function before starting treatment and regularly thereafter.
- Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
Frequently asked questions for Posaconazole
Posaconazole belongs to a class of medicines known as antifungal agents. It is used to treat serious fungal infections caused by organisms such as Aspergillus and Candida, particularly in patients who are at high risk of developing these infections. Posaconazole is mainly prescribed to severely immunocompromised individuals, such as those with cancer or those undergoing chemotherapy or blood transfusions.
Posaconazole is administered under the supervision of a doctor or nurse and should not be self-administered. The dose depends on the condition being treated and will be determined by your doctor. It is important to follow your doctor’s instructions carefully to gain the maximum benefit from Posaconazole.
Posaconazole is effective when used in the dose and duration prescribed by your doctor. Do not stop taking it even if your symptoms improve. Stopping the medication too early may cause the infection to return or worsen.
Some common side effects of Posaconazole include cough, headache, nausea, and vomiting. These side effects are generally mild and tend to resolve on their own. However, consult your doctor if any of these symptoms persist or cause concern.