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Nirmatrelvir + Ritonavir
INFORMATION ABOUT NIRMATRELVIR + RITONAVIR
Nirmatrelvir + Ritonavir Uses
Nirmatrelvir+Ritonavir is used in the treatment of Coronavirus disease (COVID-19).
How Nirmatrelvir + Ritonavir works
Nirmatrelvir + Ritonavir is a combination of two drugs, nirmatrelvir, a SARS-CoV-2-3CL protease inhibitor and ritonavir, the HIV antiretroviral. Nirmatrelvir blocks the action of SARS-CoV-2-3CL protease enzyme, which is essential for replication of the virus. On the other hand, ritonavir prevents the breakdown of nirmatrelvir.
Common side effects of Nirmatrelvir + Ritonavir
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Taste change, Diarrhea, Vomiting, High blood pressure, Muscle pain
CONTENT DETAILS
Written By
Dr. Lipika Khurana
PGDHHM, BDS
Reviewed By
Dr. Rajeev Sharma
MBA, MBBS
Last updated
18 May 2023 | 05:03 PM (UTC)
We provide you with authentic, trustworthy and revelant information
Read our editorial policy
Medicine brands for Nirmatrelvir + Ritonavir
Paxzen
₹4687 to ₹4687
Zenara Pharma
1 variant(s)
Nirmacom
₹918 to ₹918
Hetero Healthcare Limited
1 variant(s)
Expert advice for Nirmatrelvir + Ritonavir
  • Do not give Nirmatrelvir + Ritonavir to children below 12 years of age or weighing less than 40 kg.
  • Seek immediate medical attention if you see signs of allergic reactions like rash, difficulty swallowing or breathing, or swelling of the eyelids, lips, face, throat, or tongue.
  • Inform your doctor if you have liver or kidney disease before starting the treatment.
  • It is advisable to use non-hormonal contraceptive methods during the 5 days of Nirmatrelvir + Ritonavir treatment and until one menstrual cycle after stopping the drug.
  • Do not stop taking Nirmatrelvir + Ritonavir without talking to your doctor first, as it will protect you from becoming severely ill from COVID-19.
  • Even after the treatment, continue practicing COVID-appropriate behavior such as wearing a mask, social distancing, and frequent handwashing.
Frequently asked questions for Nirmatrelvir + Ritonavir
Yes, taking Nirmatrelvir+Ritonavir may make the medicines used to treat HIV less effective. It is advisable to take Nirmatrelvir+Ritonavir only if prescribed by a doctor. Do not self-medicate.
No. Avoid taking any other medicines while taking Nirmatrelvir+Ritonavir, unless otherwise prescribed by your doctor. This is because certain medicines may interact with Nirmatrelvir+Ritonavir or affect its effectiveness. Ask your doctor before taking any medicine.
Yes. Always take Nirmatrelvir+Ritonavir in the prescribed schedule which is of 5 days. Skipping your dose may affect viral clearance and worsen your condition. Also, maintain isolation and take all the preventive measures like washing your hands, wearing a mask, using a hand sanitizer regularly, etc., to minimize the risk of viral transmission.
If you miss a dose of Nirmatrelvir+Ritonavir within 8 hours of the usual time, take it as soon as possible and resume the normal dosing schedule. If it is more than 8 hours, do not take the missed dose and instead take the next schedules dose at the regular time. Do not double the dose to make up for a missed dose.
Yes. Few patients may be allergic to Nirmatrelvir+Ritonavir, just like any other medicine. If you notice any signs like rashes, hives or any other skin reactions, difficulty in breathing or swallowing, any sudden swelling like swelling of the face, lips, tongue, tightness of the throat or hoarseness of voice, it may be due to an allergic reaction. Inform your doctor immediately or rush to a nearby hospital/doctor to avoid any mishap.
No. Nirmatrelvir+Ritonavir is not safe for children as its effects have not been studied in children or those below 18 years of age.
Yes. Nirmatrelvir+Ritonavir contains lactose, a form of sugar. If you are allergic to lactose or sugar, please inform your doctor before taking Nirmatrelvir+Ritonavir.