Myo-Inositol + L-Methyl Folate Calcium + Vitamin D3 + Melatonin is a combination of four medicines : Myo-Inositol, L-Methyl Folate Calcium, Vitamin D3, and Melatonin. Myo-inositol works by relaxing the blood vessels and improving blood flow to the legs, toes and fingers, thereby relieving pain. L-Methyl Folate Calcium is a nutritional supplement that provides essential nutrients to our body and improves overall health. Vitamin D3 is a form of vitamin D. It raises vitamin D levels in your blood. This in turn raises calcium levels in your blood by helping you absorb more calcium from food. Melatonin is a natural hormone which regulates the sleep-wake cycle and helps you fall asleep.