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Mifepristone + Misoprostol
INFORMATION ABOUT MIFEPRISTONE + MISOPROSTOL
Mifepristone + Misoprostol Uses
Mifepristone+Misoprostol is used for medical abortion.
How Mifepristone + Misoprostol works
Mifepristone + Misoprostol is a combination of two medicines: Mifepristone and Misoprostol, which causes abortion. Mifepristone blocks the effects of progesterone, a natural female hormone that is needed for the pregnancy to sustain. Without this hormone, the lining of the uterus (womb) breaks down as it does during a menstrual period and stops the growth of the pregnancy. Misoprostol increases contractions of the uterus to cause abortion.
Common side effects of Mifepristone + Misoprostol
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Nausea, Vomiting, Diarrhea, Weakness, Fever, Chills, Headache, Heavy bleeding, Uterine cramps
CONTENT DETAILS
Written By
Dr. Nitika Makhija
MDS, BDS
Reviewed By
Dr. Lalit Kanodia
MBA, MD Pharmacology
Last updated
12 Sep 2022 | 06:55 AM (UTC)
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Expert advice for Mifepristone + Misoprostol
  • Mifepristone + Misoprostol helps terminate a pregnancy.
  • Use caution while driving or doing anything that requires concentration as it can cause dizziness and sleepiness.
  • It does not affect fertility. Use contraception to avoid pregnancy.
  • For pregnancy termination:
    • Take it no later than 63 days after the first day of your last menstrual period.
    • Take Misoprostol 36 – 48 hours after taking Mifepristone.
    • Rest for at least 3 hours after taking the Misoprostol.
    • Take it only as prescribed by the doctor. Miscarriages, if incomplete, may result in serious medical complications leading to hospitalization, surgery and possible infertility.
    • Vaginal bleeding lasting for approximately 12 days may occur after taking this medicine. Inform your doctor immediately if excessive bleeding occurs or if you suffer from severe abdominal pain.
Frequently asked questions for Mifepristone + Misoprostol
Mifepristone+Misoprostol are the medicines, used for medical termination of pregnancy. They are only used to terminate a pregnancy which should not be more than 63 days old, counting from the first day of the last menstrual period.
Mifepristone+Misoprostol should only be taken as per the advice of the doctor. The course is started with Mifepristone. Misoprostol is advised after 36-48 hours of taking Mifepristone. However, Misoprostol should only be taken under the supervision of a gynecologist, at a clinic or hospital setting.
After taking Mifepristone, you may or may not experience vaginal bleeding. However, you may experience abdominal cramping, diarrhea, stomach pain, and nausea immediately after taking Misoprostol. You may also have vaginal bleeding within 4 hours of taking Misoprostol. You may also be asked to stay at the clinic or healthcare center for at least 3 hours after taking this medicine. After 14 days of taking Mifepristone (pill you took before Misoprostol), your gynecologist may run some blood tests or perform ultrasonography to confirm whether pregnancy has been terminated or not.
No, studies have shown that this medicine does not impair the fertility of the women. Your future chances of getting pregnant are as equal as those who have not taken this medicine.
The common side effects of using Mifepristone+Misoprostol are abdominal pain, abdominal cramping, nausea, diarrhea, dizziness, uterine contractions, pelvic pain, and shivering. If you experience a very heavy vaginal bleeding or if any of these side effects bother you please consult with your gynecologist.