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Hyoscyamine
INFORMATION ABOUT HYOSCYAMINE
Hyoscyamine Uses
Hyoscyamine is used for pain relief.
How Hyoscyamine works
Hyoscyamine is an anti-muscarinic. It works by decreasing the stomach secretions such as mucus and acids to relax the gut muscles. By doing this, it relieves abdominal cramps and pain.
Common side effects of Hyoscyamine
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Constipation, Dizziness, Drowsiness, Difficulty in urination, Headache, Blurred vision, Flushing (sense of warmth in the face, ears, neck and trunk), Confusion, Dilatation of pupil, Difficulty in swallowing, Slow heart rate, Vomiting, Nausea, Blisters on fingers/feet, Dry skin, Rash, Psychotic disorder, Delirium (acute confusional state), Hallucination, Loss of consciousness, Neuroleptic malignant syndrome, Photophobia, Glaucoma, Palpitations, Arrhythmia (irregular heartbeats), Hypotension (low blood pressure), Injection site pain, Feeling thirsty
CONTENT DETAILS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Lalit Kanodia
MBA, MD Pharmacology
Last updated
10 Apr 2025 | 04:36 AM (UTC)
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Expert advice for Hyoscyamine
  • Hyoscyamine is used to treat stomach and intestinal disorders, like peptic ulcer disease and irritable bowel syndrome.
  • Hyoscyamine is used to treat many different stomachs and intestinal disorders, including peptic ulcer and irritable bowel syndrome.
  • Before taking Hyoscyamine, inform your doctor if you have urination problems, an enlarged prostate, a stomach or bowel obstruction (including paralytic ileus), GERD, or severe ulcerative colitis.
  • Avoid taking antacids at the same time you take Hyoscyamine. Antacids can make it harder for your body to absorb Hyoscyamine. If you use an antacid, take it after 2 hours of taking Hyoscyamine.
  • Avoid becoming overheated or dehydrated during exercise and in hot weather. Hyoscyamine can decrease sweating and you may be more prone to heatstroke.
  • Tell your doctor if you are pregnant or plan to become pregnant.
  • It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Frequently asked questions for Hyoscyamine
No. Hyoscyamine is not an over the counter (OTC) drug. It can be obtained only on producing a valid prescription
No. It does not have a chemical structure or effects similar to steroids or sulfa drugs
Hyoscyamine blocks the action of a chemical called acetylcholine, and relaxes muscles of stomach and intestine and provides relief from abdominal cramps
However, by reducing muscle contractions it provides relief from pain due to cramps
Hyoscyamine has no known harmful interaction with active ingredients in Benadryl, Xanax (alprazolam), Prevacid (lansoprazole), omeprazole, ibuprofen, Tylenol (acetaminophen) or Aleve (naproxen). Please inform your doctor about all medication you are currently taking to avoid any harmful drug interaction
Concomitant use of Hyoscyamine with Imodium (loperamide), Bentyl (dicyclomine) and Percocet (acetaminophen + oxycodone) can cause harmful drug interactions and should be avoided. Please inform your doctor about all medication you are currently taking to avoid any harmful drug interaction
Treatment with Hyoscyamine may be helpful in controlling diarrhea associated with bowel spams; however, it can aggravate constipation. Contact your doctor immediately if you experience diarrhea as a side effect of Hyoscyamine treatment
Hyoscyamine may provide relief from gas or nausea if they are symptoms of intestinal bowel syndrome or other gastrointestinal problems for which Hyoscyamine is given as a treatment. Nausea is also a common side effect of Hyoscyamine treatment
Constipation is a common side effect of Hyoscyamine treatment.