Glimepiride + Metformin + Vitamin D3

Glimepiride+Metformin+Vitamin D3 is a combination of three medicines: Glimepiride, Metformin and Vitamin D3. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It lowers the blood glucose levels when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Vitamin D3 is a nutrient which helps to improve the body's sensitivity to insulin.

The use of Glimepiride+Metformin+Vitamin D3 is associated with common side effects like nausea, altered taste, diarrhea, stomach pain, headache, hypoglycemia (low blood sugar level) and respiratory tract infection.

Yes, the use of Glimepiride+Metformin+Vitamin D3 can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, do more than routine exercise or take other antidiabetic medicines along with it. So, regular monitoring of blood sugar level is important. Always carry glucose tablets, honey or fruit juice with you.

The use of Glimepiride+Metformin+Vitamin D3 should be avoided in patients with known allergy to any of the components or excipients of this medicine. It should also be avoided if you have an active liver disease indicated by high levels of transaminase levels in the body.

Vitamin D is a fat-soluble vitamin and has an important role in the body. It not only helps to maintain the health of your bones, teeth and joints but also helps to prevent diabetes. Vitamin D is known to improve the body's sensitivity to insulin, the hormone which regulates blood sugar levels, thereby reducing the risk of insulin resistance. Insulin resistance is often a precursor to type 2 diabetes.

Yes, the use of Glimepiride+Metformin+Vitamin D3 can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Glimepiride+Metformin+Vitamin D3 and immediately consult your doctor.

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.