Equine Rabies Immunoglobulin is more economical as compared to human rabies immunoglobulin (HRIG) and hence more affordable to patients in developing countries, like India. However, Equine Rabies Immunoglobulin may cause anaphylaxis (a severe, potentially life-threatening allergic reaction), serum sickness and other allergic reactions and thus, physicians are hesitant to use it.

Rabies is a 100% preventable disease. Proper wound management and simultaneous administration of Equine Rabies Immunoglobulin combined with anti-rabies vaccine (ARV) is almost invariably effective in preventing rabies, even after high-risk exposure.

Equine Rabies Immunoglobulin is not required for patients who have previously received a complete vaccination series of rabies.

Equine Rabies Immunoglobulin should be administered into the muscle (the intramuscularly). If a large volume (> 2mL for children or > 5 mL for adults) is required, it is advised to divide the doses and for each dose a different site should be used. The immunoglobulin and the anti-rabies vaccine should be administered at two different sites of the body.

Whether Equine Rabies Immunoglobulin is painful or not depends on your pain tolerance. During your initial treatment, a healthcare professional will put Equine Rabies Immunoglobulin in the area where you were bitten which can be painful. Therefore, you may need a relatively greater amount of Equine Rabies Immunoglobulin may be required to be placed in and around the wound site to ease out your pain and treat infection.