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Dimethyl fumarate
INFORMATION ABOUT DIMETHYL FUMARATE
Dimethyl fumarate Uses
Dimethyl fumarate is used in the treatment of multiple sclerosis (MS).
How Dimethyl fumarate works
Dimethyl fumarate is an Nrf2 activator. It works by suppressing inflammation and immune response that cause nerve damage in multiple sclerosis.
Common side effects of Dimethyl fumarate
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Flushing (sense of warmth in the face, ears, neck and trunk), Nausea, Diarrhea, Nasopharyngitis (inflammation of the throat and nasal passages), Urinary tract infection, Upper respiratory tract infection, Abdominal pain, Protein in urine, Vomiting, Itching, Rash, Hot flashes, Increased alanine aminotransferase, Gastroenteritis, Dyspepsia, Erythema (skin redness), Microalbuminuria, Dryness in mouth, Hypersensitivity, Weight loss, Allergic dermatitis, Otitis media (infection of ear), Lymphocytopenia
CONTENT DETAILS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Lalit Kanodia
MBA, MD Pharmacology
Last updated
28 Mar 2025 | 06:23 AM (UTC)
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Expert advice for Dimethyl fumarate
  • Dimethyl fumarate helps treat multiple sclerosis.
  • Take it with food to avoid an upset stomach.
  • Do not chew, crush or break the tablets as they have a special coating  to help prevent irritation of your stomach.
  • Do not consume alcohol while taking this medicine as it may worsen the side effects.
  • Your doctor may get regular blood and urine tests done to monitor your blood cells, kidney and liver function during treatment with this medicine. 
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
  • Do not take Dimethyl fumarate if you are pregnant or breastfeeding. Use a reliable contraceptive method to prevent pregnancy.
  • Dimethyl fumarate helps treat multiple sclerosis.
  • Take it with food to avoid an upset stomach.
  • Do not chew, crush or break the tablets as they have a special coating  to help prevent irritation of your stomach.
  • Do not consume alcohol while taking this medicine as it may worsen the side effects.
  • Your doctor may get regular blood and urine tests done to monitor your blood cells, kidney and liver function during treatment with this medicine. 
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
  • Do not take Dimethyl fumarate if you are pregnant or breastfeeding. Use a reliable contraceptive method to prevent pregnancy.