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Chlorambucil
INFORMATION ABOUT CHLORAMBUCIL
Chlorambucil Uses
Chlorambucil is used in the treatment of Hodgkin’s disease and blood cancer.
How Chlorambucil works
Chlorambucil is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.
Common side effects of Chlorambucil
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Bone marrow suppression
CONTENT DETAILS
Written By
Dr. Anuj Saini
MMST, MBBS
Reviewed By
Dr. Lalit Kanodia
MBA, MD Pharmacology
Last updated
28 Mar 2025 | 05:43 AM (UTC)
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Expert advice for Chlorambucil
  • Chlorambucil should be taken one hour before a meal or two hours after a meal. 
Frequently asked questions for Chlorambucil
Chlorambucil is administered orally in tablet form.
Chlorambucil belongs to a class of drugs called nitrogen mustard derivatives which kill the cancer cells by interfering with DNA replication, and also by directly slowing or stopping their growth.
No, hair loss or constipation has not been reported with the use of Chlorambucil.
Chlorambucil is used to treat some types of blood cancers like Hodgkin's disease (cancer that starts in blood cells that are part of immune system), certain forms of non-Hodgkin's lymphoma, chronic lymphocytic leukemia (disease where the bone marrow produces a large number of abnormal white cells. It is also used to treat Waldenstrom's macroglobulinaemia (rare blood condition involving the release of an abnormal protein, macroglobulin, into the blood).
Chlorambucil is metabolized in liver to form nontoxic compounds which are excreted in urine.
Chlorambucil has to be stored in a refrigerator at a temperature between 2 °C – 8 °C.