Buprenorphine+Naloxone is used in opioid dependence.

Buprenorphine + Naloxone is a combination of two medicines: buprenorphine and naloxone which treat opioid addiction. Buprenorphine is an opioid partial agonist. It prevents withdrawal symptoms in patients who stop taking opioid drugs by producing similar effects to these drugs. Naloxone is an opioid antagonist which blocks the opioid receptors to prevent withdrawal side effects.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them