Azelaic Acid+Tretinoin is used in the treatment of melasma.

Azelaic Acid + Tretinoin is a combination of two medicines: Azelaic Acid and Tretinoin which treat melasma (dark spots on skin). Azelaic Acid is a naturally occurring acid. It works by blocking an enzyme (tyrosinase) which stimulates the production of melanin, a skin-darkening pigment. It also reduces the formation of harmful chemicals (free radicals) that cause pigmentation. Tretinoin is a form of vitamin A that helps the skin to renew itself more quickly.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them