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Aspirin + Clopidogrel
INFORMATION ABOUT ASPIRIN + CLOPIDOGREL
Aspirin + Clopidogrel Uses
Aspirin+Clopidogrel is used to prevent prevention of heart attack and stroke. It decreases the chances of having another heart attack or stroke from a disease related to your heart or blood vessels.
How Aspirin + Clopidogrel works
Aspirin + Clopidogrel is a combination of two antiplatelet medicines: Aspirin and Clopidogrel which prevent heart attack.
Common side effects of Aspirin + Clopidogrel
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Abdominal pain, Bruise, Diarrhea, Gastrointestinal bleeding, Increased bleeding tendency, Nosebleeds, Dyspepsia, Stomach inflammation, Nausea, Vomiting, Constipation, Flatulence
CONTENT DETAILS
Written By
Dr. Nitika Makhija
MDS, BDS
Reviewed By
Dr. Lalit Kanodia
MBA, MD Pharmacology
Last updated
13 Jun 2023 | 11:29 AM (UTC)
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Expert advice for Aspirin + Clopidogrel
  • You have been prescribed Aspirin + Clopidogrel to lower your risk of heart attack and stroke.
  • Take it with food to avoid an upset stomach. 
  • It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails or using sharp objects.
  • Let your doctor know you are taking Aspirin + Clopidogrel before undergoing any surgical procedure.
Frequently asked questions for Aspirin + Clopidogrel
You may have been prescribed Aspirin+Clopidogrel if you had a heart attack, were treated with stents in your coronary arteries, or had coronary artery bypass graft surgery (CABG).
Yes, Aspirin+Clopidogrel is a type of blood thinner. It works by preventing platelets (type of blood cells) from sticking together and forming clots. This action of Aspirin+Clopidogrel helps in preventing conditions like heart attack or stroke in people with heart disease, who have recently suffered a heart attack or severe heart-related chest pain (unstable angina).
It is not advised to take alcohol while taking Aspirin+Clopidogrel, as alcohol may increase your chance of stomach bleeding. As a result, you may vomit blood (which may be bright red blood or black/dark brown like coffee grounds) or you may have bloody or black tarry stools. Discuss with your doctor if you are not sure.
Your doctor will decide whether you need to stop taking Aspirin+Clopidogrel before any surgery or treatment or not. Usually, if a surgery or treatment is planned beforehand, the doctor may stop Aspirin+Clopidogrel a few days (usually 7 days) before the surgery or treatment owing to the increased risk of bleeding during the procedure. You should not stop taking Aspirin+Clopidogrel on your own without discussing it with your doctor.
Aspirin+Clopidogrel may cause serious or life-threatening bleeding. Moreover, you may bruise easily and it may take longer than usual for bleeding to stop even if you have a minor injury like a small cut while shaving. Get emergency medical help if you notice excessive or prolonged bleeding. You should inform your doctor if you notice black tarry stools or if there is blood in the urine. Be vigilant on any signs of stroke such as sudden numbness or weakness (one side or both sides of the body), difficulty walking, mental confusion, slurred speech, dizziness and any unexplained headache. Contact your doctor immediately if you develop any such signs of stroke as stroke is an uncommon side effect of Aspirin+Clopidogrel and needs urgent medical attention as it can otherwise be fatal.
Aspirin+Clopidogrel is not recommended for people who are allergic to it or any of its ingredients. Do not take Aspirin+Clopidogrel if you have or ever had severe liver disease, stomach ulcers, bleeding in the brain (stroke or a transient ischemic attack, also known as TIA), or if you have a bleeding disorder known as hemophilia (disease in which blood does not clot normally). Additionally, avoid taking Aspirin+Clopidogrel if you are trying to get pregnant, already pregnant, or breastfeeding.
If you forget to take a dose of Aspirin+Clopidogrel, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Your doctor will suggest the exact duration for which you may have to take Aspirin+Clopidogrel. The duration will be decided after considering various factors like the illness you are being treated for, type of stent inserted, any episodes of bleeding experienced by you during treatment, etc. Usually, Aspirin+Clopidogrel is prescribed for a minimum duration of 1 year. However, it is advised to follow your doctor's advice precisely to get maximum benefit of Aspirin+Clopidogrel. Do not stop the medication on your own, consult your doctor first. Sudden discontinuation may increase the chances of clot formation in the stent, heart attack and can even lead to death.
Avoid activities that may increase your chances of bleeding. Be extra careful while shaving or brushing your teeth to prevent bleeding. Also, you should avoid taking painkillers, but if you need to take one like ibuprofen for joint pain, headache, backache, etc. then consult your doctor first. This is because taking pain killers with Aspirin+Clopidogrel may increase your chances of developing a stomach ulcer and bleeding. Refrain from taking excessive alcohol with Aspirin+Clopidogrel as it can irritate your stomach and lead to a stomach ulcer as well.