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Apalutamide
INFORMATION ABOUT APALUTAMIDE
Apalutamide Uses
Apalutamide is used in the treatment of prostate cancer.
How Apalutamide works
Prostate cancer cells depend on androgens to grow and survive. Even in cases where the cancer becomes resistant to standard hormonal therapies (castration-resistant), androgen receptors in the cancer cells continue to be active and promote cancer growth. Apalutamide targets these androgen receptors, blocks their activation, and prevents them from binding to androgens. This action inhibits the signaling pathway that drives the growth and proliferation of prostate cancer cells.
Common side effects of Apalutamide
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Joint pain, Diarrhea, Fatigue, Skin rash, High blood pressure, Flushing (sense of warmth in the face, ears, neck and trunk), Fall, Weight loss
CONTENT DETAILS
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Written By
Dr. Subita Alagh
BDS
Reviewed By
Dr. Rajeev Sharma
MBA, MBBS
Last updated
30 Oct 2025 | 10:22 AM (UTC)
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Medicine brands for Apalutamide
Expert advice for Apalutamide
- If you have ever experienced a seizure, you must inform your doctor!
- If you have ever suffered from a brain injury, stroke (within one year), or primary brain tumor, inform your doctor.
- Inform your doctor if you have a history of cardiovascular problems.
- Follow your doctor's instructions regarding the dosage, timing, and duration of the treatment.
- Attend all follow-up visits with your doctor as scheduled.
- The doctor may monitor your liver function while you are on Apalutamide treatment, as it can affect liver enzymes.
- You have been prescribed Apalutamide for the treatment of prostate cancer.
- Take it with or without food, preferably at the same time every day.
- Do not drive or do anything requiring concentration unless you know how Apalutamide affects you.
- It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
- If you are diabetic, monitor your blood glucose regularly while taking Apalutamide.
- Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
- Do not stop taking the medication without talking to your doctor first.