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Acyclovir Topical



Acyclovir topical is used to treat cold sores (fluid filled blister on and around the lips) and infections of the skin, eye and genitals caused by herpes simplex and herpes zoster virus. It can also be used to treat chickenpox caused by varicella-zoster virus. 

How it works

Acyclovir topical belongs to the class of medications called as antivirals. It prevents the synthesis of viral DNA and thereby slows down the growth and spread of the virus.

Common side effects

Application site burning, Application site pain, Application site tingling, Irritation, Skin inflammation


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Expert advice

  • Wash your hands before and after using acyclovir cream. Wash and dry the affected area before applying the cream/ointment. 
  • Avoid direct contact of cream with your eyes. In case of direct contact, wash your eyes with water and seek immediate medical attention.
  • Inform your doctor before using acyclovir topical, if you have conditions that can make your immune system weak such as HIV, AIDS or bone marrow transplantation.
  • Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding. 
  • Do not use if you are allergic to acyclovir or any of its ingredients.

Frequently asked questions

Acyclovir Topical

Q. Is acyclovir topical effective?
Acyclovir topical is an antiviral drug used to treat infections caused by herpes simplex virus. It is effective if used as advised by your doctor. The effectiveness of acyclovir may vary upon individual response.
Q. Is Acivir cream same as acyclovir cream?
Acivir is a trade name for active drug acyclovir.
Q. Is Zovirax a steroid?
Zovirax is a trade name for active drug acyclovir. It is not a steroid.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)