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Isoniazid + Pyrazinamide + Rifampicin
INFORMATION ABOUT ISONIAZID + PYRAZINAMIDE + RIFAMPICIN
Isoniazid + Pyrazinamide + Rifampicin Uses
Isoniazid+Pyrazinamide+Rifampicin is used in the treatment of tuberculosis.
How Isoniazid + Pyrazinamide + Rifampicin works
Isoniazid + Pyrazinamide + Rifampicin is a combination of three medicines: Isoniazid , Pyrazinamide and Rifampicin which treat tuberculosis. Isoniazid prevents the TB bacteria from forming their own protective covering while Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by these bacteria to make essential proteins and to reproduce. Together, they kill the bacteria and eradicate the infection. Pyrazinamide , on the other hand works by slowing the growth of these bacteria.
Common side effects of Isoniazid + Pyrazinamide + Rifampicin
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Nausea, Vomiting, Peripheral neuropathy (tingling and numbness of feet and hand), Abdominal pain, Skin rash, Hepatitis (viral infection of liver), Lethargy, Low blood platelets, Thrombocytopenic purpura, Cutaneous reactions
CONTENT DETAILS
Last updated
25 May 2023 | 06:41 AM (UTC)
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Medicine brands for Isoniazid + Pyrazinamide + Rifampicin
Expert advice for Isoniazid + Pyrazinamide + Rifampicin
- Isoniazid + Pyrazinamide + Rifampicin should be taken on an empty stomach but at the same time every day.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Isoniazid + Pyrazinamide + Rifampicin affects you.
- Avoid drinking alcohol while taking this medicine as this may increase the risk of side effects on the liver.
- Avoid taking hormone-based birth control methods as Isoniazid + Pyrazinamide + Rifampicin may decrease their effectiveness.
- Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.