Fecal Calprotectin, Stool
Understanding Fecal Calprotectin, Stool
What is Fecal Calprotectin, Stool?
The Fecal Calprotectin, Stool test measures the level of calprotectin, a protein released by white blood cells, in the stool or feces. This test detects inflammation in the intestines and can help diagnose and monitor inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis.
Fecal matter/stool can provide important information about conditions affecting your gut or gastrointestinal (GI) tract. The Fecal Calprotectin, Stool test is a non-invasive biomarker that allows the evaluation of intestinal inflammation caused by conditions like inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, and differentiates it from other non-inflammatory diseases, such as irritable bowel syndrome (IBS). Fecal Calprotectin may also be associated with other disorders such as celiac disease, colorectal cancer, and gastrointestinal infections, which also show inflammation of the gut.
The Fecal Calprotectin, Stool test can help differentiate between inflammatory and non-inflammatory bowel conditions. Higher than normal amounts of fecal calprotectin are usually associated with active inflammatory diseases, while lower levels indicate other non-inflammatory conditions. Additionally, this test can be used to monitor the effectiveness of ongoing treatment for IBD, look for recurrence or relapse, and adjust treatment plans accordingly. This test can also help determine whether an endoscopy is indicated if IBD is suspected.
Your doctor may suggest getting the Fecal Calprotectin, Stool test if you notice symptoms of IBD, such as chronic diarrhea, abdominal pain, rectal bleeding, weight loss, and fatigue. The test is not a specific or diagnostic test for IBD but may help evaluate the degree of inflammation. It should be noted that additional blood and stool tests may be performed if the doctor suspects certain conditions that might be causing the symptoms.
It is advisable to avoid alcohol, nicotine-containing products, and certain medications like anti-inflammatory drugs before getting tested to maintain test accuracy. No other special preparations are required before getting the Fecal Calprotectin, Stool done. However, you are still advised to follow your doctor's instructions closely.
Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. Narrate your complete medical history to help the doctor correlate your clinical and laboratory findings. The results will help them determine your medical condition and formulate your treatment plan.
What is Fecal Calprotectin, Stool used for?
The Fecal Calprotectin, Stool test is done to:
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Detect inflammation in the intestine if you exhibit symptoms like bloody or watery diarrhea or abdominal cramps, with or without fever, lasting more than a few days.
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Differentiate IBD from irritable bowel syndrome (IBS).
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Monitor and manage ongoing treatment for IBD.
What does Fecal Calprotectin, Stool measure?
The Fecal Calprotectin, Stool test determines the amount of a protein called calprotectin that is released by neutrophils (a type of white blood cell). Whenever there is inflammation in the gastrointestinal tract, neutrophils move to the particular area and release calprotectin, resulting in an increased level in the stool. Therefore, this test is a great way to detect inflammation in the intestine.