Zero contains sucralose. Sugar substitutes are loosely considered any sweetener that you use instead of regular table sugar (sucrose). Artificial sweeteners are just one type of sugar substitute. Artificial sweeteners are synthetic sugar substitutes, but may be derived from naturally occurring substances, including herbs or sugar itself. Zero is a sugar substitute for phenylketonurics. It is heat stable cold stable suitable for baking, cooking and making desserts. No bitter after taste. It is safe for diabetics. It is a good sugar substitute; one such tablet can be easily used for preparing one cup of hot beverages like tea or coffee.