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29 Nov 2023 | 06:55 PM (IST)

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Uptonin Nasal Spray

Prescription Required
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Uptonin Nasal Spray is a medicine used for the treatment of osteoporosis in postmenopausal women. It makes the bones stronger and lowers the risk of fractures. It may also be used for bone pain associated with Paget's disease.

Uptonin Nasal Spray should be used as you have been advised by your doctor. Normally you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other, and then sniff hard to make sure it reaches deep into the nose. Then repeat for the other nostril. You should take adequate supplements of calcium and vitamin D while on the treatment of this medicine to make it more effective.

The most common side effects of this medicine include runny nose, nose bleed, back pain, joint pain, headache, and other nose symptoms such as itching, irritation, and discomfort. These are usually mild but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

Uses of Uptonin Nasal Spray

Benefits of Uptonin Nasal Spray

In Post menopausal osteoporosis

Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause. This condition can be treated with bone-strengthening medicines. Uptonin Nasal Spray slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. Use it as advised by the doctor and follow your doctor’s instructions carefully.

In Paget's disease

Paget’s disease is a condition that disrupts the replacement of old bone tissue with new bone tissue. Uptonin Nasal Spray decreases the bone degeneration and helps in regeneration of healthy bone tissue. You can help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.

Side effects of Uptonin Nasal Spray

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Uptonin

  • Runny nose
  • Nosebleeds
  • Nasal irritation
  • Back pain
  • Joint pain
  • Headache

How to use Uptonin Nasal Spray

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.

How Uptonin Nasal Spray works

Uptonin Nasal Spray is a calcitonin receptor agonist. It acts by suppressing the activity of osteoclasts, cells that cause destruction of bone, thereby strengthening the bones and minimizing the risk of fractures.

Safety advice

Alcohol
No interaction found/established
Pregnancy
CONSULT YOUR DOCTOR
Uptonin Nasal Spray may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Uptonin Nasal Spray is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established

What if you forget to take Uptonin Nasal Spray?

If you miss a dose of Uptonin Nasal Spray, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Uptonin Nasal Spray
₹1567/Nasal Spray
₹2148.36/nasal spray
30% costlier
Gemcal Nasal Spray
Alkem Laboratories Ltd
₹2180/nasal spray
32% costlier
₹2300/nasal spray
39% costlier
Calnasal Nasal Spray
Koye Pharmaceuticals Pvt ltd
₹2030/nasal spray
23% costlier

Quick tips

  • You have been prescribed Uptonin Nasal Spray to make your bones stronger, and lower the risk of fractures.
  • It is used in women with osteoporosis who have undergone menopause.
  • It may cause temporary dizziness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Unopened bottles should be stored in the refrigerator. Once opened, they should be stored at room temperature for up to 35 days.
  • Stop using it and inform your doctor if you get any nosebleeds or notice any ulceration inside your nose.
  • Discontinue Uptonin Nasal Spray and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Fact Box

Chemical Class
Hormones
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Bone resorption inhibitors- Calcitonin

Patient concerns

arrow
I had hot flash, sweating and ganrahat
Dr. Pushkar Mani
Physician
Seems like post menopausal syndrome. Visit a gynaecologist.
Ovaries taken out chest pain and intense sweat high heart beats
Dr. Suman Rao
Obstetrics and Gynaecology
These are the symptoms of menopause. Consult a gynaec nearby and discuss about post menopausal therapy
arrow

User feedback


FAQs

Q. Does Uptonin Nasal Spray need to be refrigerated?

Yes, an unopened bottle of Uptonin Nasal Spray need to be refrigerated. It should be kept at a temperature between 2°C and 8°C. Do not freeze. After opening the bottle of Uptonin Nasal Spray, store it at room temperature between 15°C and 30°C.

Q. Does Uptonin Nasal Spray increase bone density?

Uptonin Nasal Spray contains calcitonin which is a hormone that is naturally produced by the thyroid gland and is responsible for maintaining calcium balance in the body. Uptonin Nasal Spray decreases the bone loss and damage in patients with osteoporosis. In some cases, it also helps in bone formation by activating the bone forming cells, thereby increasing the bone density.

Q. Can Uptonin Nasal Spray reduce the calcium levels in blood?

Yes, Uptonin Nasal Spray can reduce the levels of calcium in the blood. If the calcium levels in your blood drop down severely then it can present with numbness or tingling in your fingers, toes, or around your mouth. The blood calcium levels need to be monitored in such cases. Immediately contact your doctor if you experience any such symptoms.

Q. How should I use Uptonin Nasal Spray?

Follow the directions given by your prescriber and do ask him in case of any doubts. Usually, it is to be given in single nostril once daily. To start with we take 1 spray in left nostril on day 1, followed by right nostril on the second day. Continue to take the medicine inside the nose by switching nostrils every alternate day. Each bottle is set to deliver 30 doses. Do not use the bottle after 30 days.

Q. Is it fine to use Uptonin Nasal Spray in pregnant women?

Generally, Uptonin Nasal Spray is not recommended for pregnant women. However, enough evidence is not available to suggest risk associated with the use of Uptonin Nasal Spray causing birth defects or miscarriage in pregnant women. Uptonin Nasal Spray should be used in pregnant women with utmost caution. It is used only if the prescribing doctor finds potential benefit to be much larger than the risk involved.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 758, 766.
  2. Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1283-84, 1294.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 184-85.
  4. Drugs.com. Calcitonin. [Accessed 02 Apr. 2019] (online) Available from:External Link
  5. Calcitonin. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2011. [Accessed 02 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Viilbery Healthcare Pvt Ltd
Address: Viilbery Healthcare Pvt. Ltd. Plot No. P- 64, Milap Nagar, M. I. D. C Residential Zone Near AIMS Hospital, Dombivili, East, Thane - 421 203, Maharashtra, India.
Country of origin: India

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