Rifampicin + Isoniazid is a combination of two antibiotics: Rifampicin + Isoniazid1 and Rifampicin + Isoniazid2, which treats tuberculosis (TB). Rifampicin + Isoniazid1 works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce. Rifampicin + Isoniazid2 prevents these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection.
You have been prescribed Ticinex for the treatment of tuberculosis.
Finish the full course of the medication, even if you feel better. Stopping it early may make the infection come back.
Take it on an empty stomach, preferably at the same time everyday.
It may discolour your urine, sweat, saliva and tears a reddish-orange colour. This is normal and not harmful.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Avoid drinking alcohol while taking Ticinex as this may increase the risk of side effects on the liver.
Use an alternative or additional contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Ticinex as it may make hormonal contraceptives such as the pill less effective.
Do not take indigestion remedies (antacids) within at least two hours of taking Ticinex.
Q. What are the instructions for storage and disposal of Ticinex?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. What is Ticinex?
Ticinex is a combination of two medicines: Rifampicin and Isoniazid. It is used in the treatment of tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by tuberculosis bacteria to make essential proteins and reproduce. Isoniazid prevents the tuberculosis causing bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection.
Q. What is the most important information I should know about the Ticinex?
Take the proper course of drug that has been prescribed to you. Do not stop in between even if you begin to feel better. Avoid alcohol while taking this medicine as it increases the risk of damage to your liver during treatment. Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.
Q. What is the best time to take Ticinex?
Take Ticinex exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.
Q. Does Ticinex cause change in urine color/turn urine orange?
Yes, Ticinex can change the color of your urine (skin, sweat, saliva, tears and feces) to brownish-red or orange. This effect is not harmful.
Q. Does the use of Ticinex make birth control pills ineffective?
Yes, Ticinex can make birth control pills less effective. So, ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm and spermicide).
Information last updated by Dr. Varun Gupta, MD Pharmacology on 19th Dec 2018. The medicine details are for information purpose only. Consult a doctor before taking any medicine.