Domperidone + Esomeprazole is a combination of two medicines: Domperidone + Esomeprazole1 and Domperidone + Esomeprazole2. Domperidone + Esomeprazole1 is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Domperidone + Esomeprazole2 is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.
Isozole D is a combination of two medicines: Domperidone and Esomeprazole. This combination is used to treat acidity and heartburn or gastroesophageal reflux disease (GERD); a condition where the acid in the stomach flows back up into the food pipe (esophagus). It is also used to treat gastric and duodenal ulcers. Domperidone helps to control vomiting by increasing the movement of the gut, allowing the food to move more easily through the stomach.
Q. Is it safe to use Isozole D?
Yes, Isozole D is safe for most of the patients. However, in some patients it may cause common side effects like diarrhoea, stomach pain, flatulence, dryness in mouth, dizziness, headache and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medicine.
Q. What is the best time to take Isozole D?
It is best to take Isozole D before the first meal of the day or on an empty stomach.
Q. Can the use of Isozole D cause abnormal heartbeat?
Yes, the use of Isozole D can increase the risk of irregular heartbeat (serious arrhythmias). This is a serious side effect but the chance that it may happen is very low. The risk may be slightly higher in those who are more than 60 years of age.
Q. What are the contraindications associated with the use of Isozole D?
The use of Isozole D is considered to be harmful for patients with a known hypersensitivity to rabeprazole or domperidone or any other inactive ingredients of the medicine. Caution is advised in patients with underlying kidney or liver disease.
Q. Can the use of Isozole D cause dry mouth?
Yes, the use of Isozole D can cause dry mouth. Dryness of mouth occurs due to Domperidone. If you experience dry mouth, drink plenty of water. Take regular sips of water during the day and keep some water on your bedside at night. Cut down the intake of alcohol and avoid smoking. If you have dry mouth, try to use alcohol-free mouthwash as its use can increase the risk of tooth decay.
Q. Can the use of Isozole D cause diarrhea?
Yes, the use of Isozole D can cause diarrhea. In case of diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and if you notice signs of dehydration, like less frequency of urination and dark colored and strong-smelling urine. Avoid taking fatty or fried foods with this medication. Also, do not take any medicines without consulting the doctor.
Q. What are the storage conditions for Isozole D?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 21st Nov 2018. The medicine details are for information purpose only. Consult a doctor before taking any medicine.