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U1-SnRNP (68 KDa) - IgG antibody

U1-SnRNP (68 KDa) - IgG antibody near me in Raigad Maharashtra

Also referred as
U1-SnRNP (68 KDa) Test
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144 hours
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The U1-SnRNP (68 KDa) - IgG antibody test is a blood test that detects antibodies against the U1 small nuclear ribonucleoprotein (snRNP) 68 KDa component. This test helps support the evaluation of autoimmune disorders, particularly systemic lupus erythematosus (SLE) and mixed connective tissue disease (MCTD). It is widely available in Raigad Maharashtra with Tata 1mg labs at an affordable price.

 

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Understanding U1-SnRNP (68 KDa) - IgG antibody

U1 small nuclear ribonucleoprotein (snRNP) is a complex of proteins and RNA found in the nucleus of cells, playing a crucial role in RNA splicing (cutting and joining pieces of RNA) and processing. In certain autoimmune conditions, the immune system produces antibodies that mistakenly target the U1-snRNP complex, particularly the 68 KDa protein component. The presence of U1-snRNP (68 KDa) antibodies in the blood suggests abnormal immune activity and is considered a significant marker for specific connective tissue diseases.

U1-snRNP antibodies are strongly linked with mixed connective tissue disease (MCTD), and their detection can help differentiate MCTD from  systemic lupus erythematosus (SLE), scleroderma, and other autoimmune disorders when interpreted with antinuclear antibody (ANA)/ Extractable Nuclear Antigens (ENA) and clinical findings. These antibodies may also appear in overlap syndromes and are not exclusive to one disease. 

The U1-SnRNP (68 KDa) - IgG antibody test is usually recommended when individuals present with symptoms such as joint pain, muscle weakness, fatigue, Raynaud’s phenomenon, unexplained fever, or skin rashes. It is often done as part of an antinuclear antibody (ANA) panel or extractable nuclear antigen (ENA) profile for comprehensive autoimmune screening.

No special preparation, such as fasting, is required for this test. However, it is important to share the complete medical history, medications, and symptoms with the doctor, as these details help in correlating results with clinical findings. If ANA (antinuclear antibody) results are available, they should also be shared, as they provide additional context for interpreting U1-SnRNP (68 KDa) - IgG antibody results. Test results should not be interpreted in isolation but in combination with other clinical and laboratory findings to support diagnosis.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate and always consult a doctor to understand the test results correctly. 

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.

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What does U1-SnRNP (68 KDa) - IgG antibody measure?

The U1-SnRNP (68 KDa) - IgG antibody test measures the presence of autoantibodies against the 68 KDa protein of the U1 small nuclear ribonucleoprotein (snRNP) complex in the blood. These antibodies indicate an abnormal immune response, where the body’s immune system mistakenly targets its own cells.

High levels of U1-SnRNP (68 KDa) antibodies are often seen in patients with mixed connective tissue disease (MCTD) and may also be present in systemic lupus erythematosus (SLE). Detecting these antibodies supports diagnosis and differentiation between different autoimmune disorders and guiding appropriate treatment. Low or absent levels are generally considered normal but must be interpreted in conjunction with other clinical findings and laboratory tests.

FAQs related to U1-SnRNP (68 KDa) - IgG antibody in Raigad Maharashtra

It is a blood test that detects antibodies against the U1 small nuclear ribonucleoprotein (68 KDa). These antibodies are linked to autoimmune diseases like mixed connective tissue disease (MCTD) and systemic lupus erythematosus (SLE).
Doctors recommend this test if you have symptoms of autoimmune disease, such as fatigue, joint pain, rashes, or muscle weakness. It helps evaluate and differentiate conditions like SLE, MCTD, and other connective tissue disorders.
A phlebotomist will clean your skin using an antiseptic alcohol cotton swab or wipe and take blood samples from your vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.
No fasting or special preparation is needed.
The test is safe. You may feel mild pain, swelling, or bruising at the site of blood collection, which usually goes away quickly.
Yes. In Raigad Maharashtra, you can schedule the U1-SnRNP (68 KDa) - IgG antibody test near you with Tata 1mg Labs. The test is easy to book, cost-effective, and available with a comprehensive report.
Yes, home sample collection for the U1-SnRNP (68 KDa) - IgG antibody test is readily available in Raigad Maharashtra. Tata 1mg Labs allows you to choose a date and time that suits your schedule for sample collection.
If you want to schedule the U1-SnRNP (68 KDa) - IgG antibody test with Tata 1mg Labs in Raigad Maharashtra, the procedure is fairly easy and hassle-free. Follow these steps to book a test: 1). Visit the Lab Tests section on the Tata 1mg website. 2). Add the test you want to the cart. 3). Pick a time and date slot according to your convenience; however, do consider the necessary prerequisites while scheduling a test. 4). You will receive a notification with all the details once the test is scheduled.
Tata 1mg Labs is a pocket-friendly platform for booking lab tests in Raigad Maharashtra. The U1-SnRNP (68 KDa) - IgG antibody test is available at an affordable price of Rs. 1429.
At Tata 1mg Labs, we understand the importance of timely results. We strive to provide fast turnaround times for test results, allowing you to get the information you need promptly. On average, we take 144 hours to provide the reports of the U1-SnRNP (68 KDa) - IgG antibody test in Raigad Maharashtra.
Content created by
Written by:
Shweta Prakash
MSc, BSc
Reviewed by:
Dr. Swati Gupta (Anand)
MD Lab Medicine, MBBS
Want to know moreRead our editorial policy
Last Updated7th Feb 2026

U1-SnRNP (68 KDa) - IgG antibody test price for other cities

Price inBangaloreRs. 1619
Price inLucknowRs. 1810
Price inAligarhRs. 1429
Price inAsansolRs. 1429
Price inChandigarhRs. 1429

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U1-SnRNP (68 KDa) - IgG antibody