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TORCH Profile IgG & IgM 10 Parameters

Also known as TORCH-10, TORCH Panel
TORCH Profile IgG & IgM 10 Parameters Includes 10 testsView All
28493000 5% Off
You need to provide
Blood
This test is for
Female
Test Preparation
  1. No special preparation is required.

Understanding TORCH Profile IgG & IgM 10 Parameters


What is TORCH Profile IgG & IgM 10 Parameters?

A TORCH Profile IgG & IgM 10 Parameters includes a series of blood tests to evaluate antibody levels (IgG and IgM) against TORCH infections. TORCH represents Toxoplasmosis(T), Rubella(R), Cytomegalovirus(C), and Herpes Simplex (H) virus infections. This test helps identify past or recent exposure to these infections, offering insights into an individual’s immune response. 

The TORCH Profile IgG & IgM 10 Parameters is a comprehensive examination tailored to detect antibodies specifically, Immunoglobulin G (IgG) and Immunoglobulin M (IgM) against a group of infectious agents collectively known as TORCH. TORCH encompasses Toxoplasma gondii, Rubella virus, Cytomegalovirus (CMV), and Herpes simplex viruses (HSV-1 and HSV-2). This profile helps assess an individual's immune response to these pathogens. IgM antibodies generally indicate recent or acute infection, while IgG antibodies suggest a past exposure or immunity. The test is particularly relevant for pregnant women, as certain TORCH infections can have serious implications for a newborn’s development.

By measuring antibody levels, doctors can identify whether an individual has been exposed to these infections and assess the timing of exposure. This information is valuable for managing and monitoring conditions, especially during pregnancy, as it helps guide appropriate interventions and care strategies. The TORCH profile thus helps understand an individual's immune status and guide clinical decisions.

Generally, no special preparation is required for a TORCH profile done. However, inform your doctor about any medications or supplements you are taking, as they might influence your test results. Also, tell your doctor about recent infections or vaccinations, as they can affect the antibody level. If you are pregnant and undergoing TORCH profile, talk to your doctor as certain antibody tests have implications for prenatal care. 

Lab test results may vary across different laboratories. Abnormal test results require an expert interpretation, therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for proper understanding of the test results. Also, tell your complete medical history, including any known allergies or autoimmune conditions, which can impact test interpretations to help the doctor correlate your laboratory and clinical findings and formulate a robust treatment plan.

What is TORCH Profile IgG & IgM 10 Parameters used for?

A TORCH Profile IgG & IgM 10 Parameters is done: 

  • As a part of preconception screening to identify any pre-existing immunity or recent infections, ensuring a healthy start to pregnancy. 

  • For pregnant women to assess exposure to TORCH infections, as certain infections have implications for fetal health. 

  • For women undergoing prenatal screening when fetal anomalies are detected, helping to understand if TORCH infections could be the contributing factor. 

  • When individuals exhibit unexplained symptoms such as fever, rash, or flu-like symptoms, prompting an investigation into potential TORCH infections. 

  • When there is a known or suspected exposure to TORCH infections, such as contact with individuals diagnosed with these infections. 

  • For those individuals with weakened immune systems, as they are more susceptible to TORCH infections. 

What does TORCH Profile IgG & IgM 10 Parameters measure?

Contains 10 tests

A TORCH Profile IgG & IgM 10 Parameters helps measure the levels of specific antibodies IgG and IgM in the blood providing insights into the immune response against TORCH infections. This test helps evaluate how the immune system has responded to infections like Toxoplasmosis, Rubella, Cytomegalovirus, and Herpes Simplex viruses over time. IgG antibodies in the blood indicate a past infection, while IgM antibodies signify an active infection. This distinction helps doctors assess the timing of exposure and the individual’s current immune status. This test plays an important role in understanding the immunity against Toxoplasmosis, Rubella, Cytomegalovirus, and Herpes Simplex viruses, helping in diagnostic evaluation, prenatal care, and overall health management. 

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Toxoplasma gondii - IgG

A Toxoplasma gondii - IgG test measures the presence of immunoglobulin G (IgG) antibodies specific to the Toxoplasma gondii parasite in the blood. These antibodies indicate a previous (past) exposure to the parasite. The presence of IgG antibodies indicates that you have had an infection, but it does not tell when. A high avidity in the IgG avidity test strongly suggests the infection happened more than 4 months ago. However, a low avidity result alone cannot be used to diagnose when the infection occurred, and further clinical evaluation is needed.

In general, having IgG antibodies to Toxoplasma gondii suggests a certain level of protection, but the effectiveness and duration of this protection can depend on factors such as the individual’s overall health, the strain of the parasite, and other immune-related considerations. 

Know more about Toxoplasma gondii - IgG

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Toxoplasma gondii - IgM

A Toxoplasma gondii - IgM test measures the presence of IgM antibodies in the blood, indicating recent or acute infection with the Toxoplasma gondii parasite. These antibodies are part of the body’s immune response and are produced when an individual is exposed to the parasite. These antibodies are the first to appear after being exposed to the parasite and may persist for up to 18 months post-infection. This test provides valuable information about recent exposure to Toxoplasma gondii, helping in the diagnosis and management of infections, especially in cases where timely detection is crucial.

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Rubella Virus - IgG

The Rubella Virus - IgG test measures the presence of Immunoglobulin G (IgG) antibodies specific to the rubella virus in an individual's blood. IgG antibodies are indicative of previous exposure or vaccination against rubella. This test helps assess an individual’s immunity status to the virus. If the IgG antibodies are detected, it suggests that the individual has either been vaccinated against rubella or has had a previous infection, leading to the development of immune protection. 

Know more about Rubella Virus - IgG

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Rubella Virus - IgM

The Rubella Virus - IgM test determines the presence of Immunoglobulin M (IgM) antibodies in the blood against Rubella virus. IgM antibodies are the first line of defense produced by the immune system in response to a recent infection. Therefore, this test is crucial for diagnosing acute or recent rubella infections. 

In acute primary infection during pregnancy, IgM may be detected 4-15 days after the rash appears. The IgM levels begin to decline after 36 -70 days and may last up to 180 days in some cases.

Know more about Rubella Virus - IgM

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Herpes Simplex Virus 1 IgM

The Herpes Simplex Virus 1 IgM test detects the presence of IgM antibodies that are produced as a body's initial response to an HSV-1 infection. They are critical in the initial control of the virus. IgM antibodies may take up to 10 days to develop. Also, these antibodies are usually present in higher concentrations shortly after infection and eventually decrease after some time (7-10 days). Therefore, the presence of HSV-1 IgM antibodies is a strong indication of recent exposure and primary infection.

Early detection allows doctors to detect symptoms quickly and provide necessary medical interventions to individuals suffering from HSV infection, leading to better outcomes and improved quality of life.

 

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Herpes Simplex Virus 1 IgG

A Herpes Simplex Virus 1 IgG test determines the presence of IgG antibodies against HSV-1 in response to the Herpes infection. The body begins to make IgG antibodies around 18 to 21 days after the exposure of the virus and remains in the body for life. The presence of IgG antibodies generally indicates past exposure and immunity against herpes infection. Getting tested helps manage herpes infection and prevent it from spreading further as the HSV-1 remains dormant in the body after the initial infection and can reactivate at various times, leading to recurrent outbreaks.

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Cytomegalovirus IgG Antibody

A Cytomegalovirus IgG Antibody test measures the presence of IgG antibodies in the blood, indicating a previous CMV infection. IgG antibodies are produced several weeks after the initial CMV infection. IgG levels rise during the active infection, then stabilize as the CMV infection resolves and the virus becomes inactive. Once exposed to CMV, you will have some measurable amount of CMV IgG antibody in your blood for the rest of your life, which provides protection from getting another primary infection (immunity). However, if you have a weak immune system, the virus can reactivate and cause serious symptoms or organ damage.

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Cytomegalovirus IgM Antibody

A Cytomegalovirus IgM Antibody test measures the presence of Immunoglobulin M (IgM) antibodies in the blood, specifically targeting the CMV. IgM antibodies are produced by the body first in response to a CMV infection. They can be detected in the blood within a week or two after the initial exposure. IgM levels rise for a short time, then decline and usually fall below detectable levels after a few months. IgM antibody levels rise again when latent CMV is reactivated.

Elevated levels of CMV IgM antibodies indicate an ongoing infection or recent exposure to the virus. Understanding the presence of IgM antibodies helps doctors diagnose and manage CMV infections effectively. 

 

Know more about Cytomegalovirus IgM Antibody

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Herpes Simplex Virus 2 IgG

A Herpes Simplex Virus 2 IgG test looks for the presence of IgG antibodies against HSV-2  in response to the Herpes infection. IgG antibodies are the most frequent type of antibody, which are developed around 18 to 21 days after the virus invades the body and remains in the body for life. Thus, the presence of IgG antibodies typically means an individual has been infected with the HSV-2 at some point. Detection of HSV-2 infection allows doctors to provide necessary support and guidance to individuals suffering from genital herpes, leading to better treatment outcomes and improved quality of life.

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Herpes Simplex Virus 2 IgM

The Herpes Simplex Virus 2 IgM test detects the presence of IgM antibodies that are produced against an infection caused by herpes simplex virus 2 (HSV-2). IgM antibodies specific for HSV-2 are present only for a relatively short period of time. They are the first antibodies to form after the infection and are excellent markers for the presence of a recently acquired or active disease. Also, these antibodies are usually present in higher concentrations shortly after infection and eventually decrease after some time (7-10 days).

Know more about Herpes Simplex Virus 2 IgM

Interpreting TORCH Profile IgG & IgM 10 Parameters results


Interpretations

The absence of antibodies indicates a negative result, while the presence of antibodies indicates a positive result.

A negative result for both IgG and IgM indicates no previous or recent infection.

The positive result for IgM and negative result for IgG indicates a very recent infection.

A positive result for IgG and negative result for IgM indicates a very old infection which may have been cured already or a vaccination.

A positive result for both IgG and IgM indicates a recent ongoing infection.

The TORCH Profile is used as a screening test and its results are confirmed with further tests.

 

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about TORCH Profile IgG & IgM 10 Parameters


Frequently Asked Questions about TORCH Profile IgG & IgM 10 Parameters

Q. When is the TORCH Profile IgG & IgM 10 Parameters recommended?

A TORCH Profile IgG & IgM 10 Parameters is recommended for pregnant women, those with symptoms pointing towards TORCH infections, individuals with weakened immune systems, and as a part of prenatal screening.

Q. How is the TORCH profile conducted?

TORCH profile is a simple blood test with minimal risk. A trained laboratory personnel (phlebotomist) will draw a blood sample from the vein and then the sample is analyzed in a laboratory to measure IgG and IgM antibody levels.

Q. Is there any risk associated with a TORCH profile?

No, there is no risk associated with TORCH profile. However, some individuals may feel a slight sting when a needle is pricked and experience some bleeding that is normal and usually not bothersome. Rarely, some individuals may also experience slight swelling or bruising at the site of the needle prick. Applying ice 3-4 times a day for about a week may help reduce swelling and bruising. If it does not get better, consult your doctor.

Q. What do abnormal TORCH profile results indicate?

Abnormal results may suggest recent or past exposure to TORCH infections. However, interpretation should be done by the doctor, and further diagnostic tests may be needed to establish a precise diagnosis.

Q. Can the TORCH profile determine the specific infection?

TORCH profile identifies antibodies against the TORCH group but does not specify the exact infection. Further testing and clinical evaluation are often required for a precise diagnosis.

Q. Can I get re-infected with a TORCH infection?

Yes, it's possible to get re-infected with certain Torch infections, especially if your immune system is compromised, as immunity may not always provide complete protection. However, the severity of reinfection can vary, and vaccination, where available, can contribute to preventing certain TORCH infections.

Q. What complications can arise from untreated TORCH infections?

Untreated TORCH infections can lead to severe complications, including birth defects in infants( if acquired during pregnancy), developmental problems, vision or hearing impairment, and in some cases, long-term health challenges. Early detection and appropriate medical interventions are important to minimize potential complications.
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TORCH Profile IgG & IgM 10 Parameters test price for other cities


Price inGurgaonRs. 2849
Price inMumbaiRs. 2849
Price inBangaloreRs. 2849
Price inNoidaRs. 3610
Price inKolkataRs. 2849
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References

  1. Jaan A, Rajnik M. TORCH Complex. [Updated 2023 Jul 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK560528/ External Link
  2. TORCH Panel [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 18 Dec. 2023]. Available From: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=torch_panel External Link
  3. Belanger BG, Lui F. Embryology, Teratology TORCH. [Updated 2023 Jul 24]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK545148/ External Link
  4. Madireddy S, Rivas Chacon ED, Mangat R. Toxoplasmosis. [Updated 2022 Sep 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK563286/ External Link
  5. Akpan US, Pillarisetty LS. Congenital Cytomegalovirus Infection. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK541003/External Link
  6. Saleh D, Yarrarapu SNS, Sharma S. Herpes Simplex Type 1. [Updated 2023 Aug 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482197/ External Link
  7. Mathew Jr J, Sapra A. Herpes Simplex Type 2. [Updated 2023 Aug 7]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554427/ External Link
  8. Ford-Jones EL. An approach to the diagnosis of congenital infections. Paediatr Child Health. 1999 Mar;4(2):109-12. [Accessed 18 Dec. 2023]. Available From: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828203/ External Link

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