PIK3CA mutation detection assay (Exon 7, 9, 20) near me in Guwahati

The PIK3CA mutation detection assay (Exon 7, 9, 20) is a genetic test that checks for specific changes (mutations) in the PIK3CA gene, especially in exons 7, 9, and 20. This gene plays a key role in the PI3K/AKT/mTOR signaling pathway, which controls how cells grow, divide, and survive. Mutations in the PIK3CA gene can lead to overactive signaling, which may cause uncontrolled cell growth and contribute to the development of cancer. PIK3CA mutations are commonly found in various types of cancers, including breast cancer, colorectal cancer, gastric cancer, glioblastoma, and lung cancer. In particular, they occur in about 40% of hormone receptor-positive, HER2-negative breast cancers. The test detects whether a pathogenic mutation is present (positive) or not detected (negative) in the tested tissue sample. The results of this test provide important information about genetic changes in the tumor, which can help guide further medical evaluation and treatment planning.

Note: One representative block of the tumor is required. However, 1-4 representative blocks of tumors are acceptable.

Disclaimer: In no event shall the liability of TATA 1MG exceed the amount of actual cost of test charges incurred by the customer as stated on the invoice issued by Tata 1mg.