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MTHFR C677T/A1298C Mutations Detection

MTHFR C677T/A1298C Mutations Detection near me in Asansol

Also referred as
MTHFR Mutation Test
Genetic Homocysteine Risk Evaluation
For men & women
Earliest reports in
192 hours
Contains
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The MTHFR C677T/A1298C Mutations Detection test is a blood test that identifies genetic variations in the MTHFR (methylenetetrahydrofolate reductase) gene. These mutations can influence how the body processes folate and homocysteine, which are crucial for cardiovascular, neurological, and reproductive health. This test helps evaluate inherited risks for conditions associated with elevated homocysteine levels and impaired folate metabolism. It is widely available in Asansol with Tata 1mg labs at an affordable price.

The MTHFR C677T/A1298C Mutations Detection test identifies genetic variations that affect folate processing and homocysteine levels, helping assess risks for cardiovascular issues, blood clots, and pregnancy complications.

This test is recommended if there are symptoms suggestive of hyperhomocysteinemia, recurrent pregnancy loss, a family history of cardiovascular disease, or unexplained blood clotting issues. It is also used to assess genetic predisposition in individuals with a history of stroke, heart attack, or vascular abnormalities. In addition, this test may be considered before or during pregnancy to guide folate supplementation and reduce the risk of neural tube defects in the fetus.

No special preparation is needed for getting the MTHFR C677T/A1298C Mutations Detection test done. However, it is preferred that you share your clinical history, current medications, and supplement use with your doctor before giving the sample, as these may influence the results.

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Understanding MTHFR C677T/A1298C Mutations Detection

MTHFR, or methylenetetrahydrofolate reductase, is an enzyme that plays a critical role in converting folate (vitamin B9) into its active form, which is necessary for proper DNA synthesis, methylation, and homocysteine metabolism. Mutations in the MTHFR gene, particularly C677T and A1298C, can reduce enzyme activity and disrupt these processes, potentially leading to elevated homocysteine levels in the blood. Elevated homocysteine is associated with an increased risk of cardiovascular diseases, pregnancy complications, and certain neurological conditions.

The MTHFR C677T/A1298C Mutations Detection test identifies genetic variations that affect folate processing and homocysteine levels, helping assess risks for cardiovascular issues, blood clots, and pregnancy complications.

This test is recommended if there are symptoms suggestive of hyperhomocysteinemia, recurrent pregnancy loss, a family history of cardiovascular disease, or unexplained blood clotting issues. It is also used to assess genetic predisposition in individuals with a history of stroke, heart attack, or vascular abnormalities. In addition, this test may be considered before or during pregnancy to guide folate supplementation and reduce the risk of neural tube defects in the fetus.

No special preparation is needed for getting the MTHFR C677T/A1298C Mutations Detection test done. However, it is preferred that you share your clinical history, current medications, and supplement use with your doctor before giving the sample, as these may influence the results.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate and always consult a doctor to understand the test results correctly. 

Please note: This is an outsourced test. The sample is collected by TATA 1MG and processed at a NABL accredited partnered lab.

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What does MTHFR C677T/A1298C Mutations Detection measure?

The MTHFR C677T/A1298C Mutations Detection test detects specific changes in the MTHFR gene. The C677T mutation can reduce the enzyme activity significantly, especially if present in two copies (homozygous), leading to higher homocysteine levels. The A1298C mutation typically has a milder effect but can still impact folate metabolism, particularly when combined with the C677T mutation.

Identifying these mutations helps understand how efficiently your body processes folate and regulates homocysteine. Abnormal results may indicate a higher risk for cardiovascular problems, blood clots, pregnancy complications, or certain neurological conditions. Doctors may recommend dietary adjustments, folate, vitamin B12, and B6 supplementation, or closer monitoring based on test results.

FAQs related to MTHFR C677T/A1298C Mutations Detection in Asansol

Doctors may recommend the MTHFR C677T/A1298C Mutations Detection test if there is a personal or family history of cardiovascular disease, stroke, recurrent pregnancy loss, or unexplained blood-clotting disorders. It may also be suggested when homocysteine levels are elevated or to guide folate supplementation during pregnancy.
Symptoms that may indicate testing include unexplained fatigue, migraine with aura, history of blood clots, recurrent pregnancy complications, or neurological issues. Individuals with a family history of cardiovascular or thrombotic disorders may also benefit from testing.
The test involves a simple blood draw, and the risk is minimal. Some people may experience minor discomfort or bruising at the puncture site, which usually resolves on its own.
No fasting is required before the test. Patients should provide a complete medical and family history, including any medications or supplements, as this helps in accurate interpretation.
A normal result means no MTHFR C677T or A1298C mutations were found. An abnormal result shows the presence of one or both mutations, which may increase the risk of high homocysteine levels. However, having a mutation does not automatically mean you have a health problem. Your doctor will evaluate the results along with your medical history and other tests to determine any risks or next steps.
Other tests that may be ordered along with the MTHFR Mutations test include homocysteine levels, factor V Leiden mutation, and prothrombin gene mutation.
Yes. In Asansol, you can schedule the MTHFR C677T/A1298C Mutations Detection test near you with Tata 1mg Labs. The test is easy to book, cost-effective, and available with a comprehensive report.
Yes, home sample collection for the MTHFR C677T/A1298C Mutations Detection test is readily available in Asansol. Tata 1mg Labs allows you to choose a date and time that suits your schedule for sample collection.
If you want to schedule the MTHFR C677T/A1298C Mutations Detection test with Tata 1mg Labs in Asansol, the procedure is fairly easy and hassle-free. Follow these steps to book a test: 1). Visit the Lab Tests section on the Tata 1mg website. 2). Add the test you want to the cart. 3). Pick a time and date slot according to your convenience; however, do consider the necessary prerequisites while scheduling a test. 4). You will receive a notification with all the details once the test is scheduled.
Tata 1mg Labs is a pocket-friendly platform for booking lab tests in Asansol. The MTHFR C677T/A1298C Mutations Detection test is available at an affordable price of Rs. 5200.
At Tata 1mg Labs, we understand the importance of timely results. We strive to provide fast turnaround times for test results, allowing you to get the information you need promptly. On average, we take 192 hours to provide the reports of the MTHFR C677T/A1298C Mutations Detection test in Asansol.
Content created by
Written by:
Dr. Lipika Khurana
BDS, PGDHHM
Reviewed by:
Dr. Swati Gupta (Anand)
MBBS, MD Lab Medicine
Want to know moreRead our editorial policy
Last Updated19th Aug 2026

MTHFR C677T/A1298C Mutations Detection test price for other cities

Price inGurgaonRs. 4369
Price inNew DelhiRs. 4369
Price inMumbaiRs. 6749
Price inBangaloreRs. 6459
Price inHyderabadRs. 6180

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MTHFR C677T/A1298C Mutations Detection