Immunotyping, Serum near me in Dispur

The Immunotyping, Serum is a specialized laboratory test performed by Capillary Electrophoresis used to detect and characterize monoclonal proteins (M-proteins or paraproteins) produced by clonal plasma cells or B lymphocytes. The test identifies the specific immunoglobulin heavy chain (IgG, IgA, IgM, IgD, or IgE) and light chain (kappa or lambda), enabling accurate classification of monoclonal gammopathies. 

The International Myeloma Working Group (IMWG) recommends serum and urine protein electrophoresis as the initial screening tests for detecting monoclonal proteins and together with immunological characterization by immunotyping or immunofixation, are considered the gold-standard laboratory methods for the diagnosis and monitoring of multiple myeloma and related plasma cell disorders. When a monoclonal protein is detected or suspected, Immunotyping is performed to confirm and accurately identify the immunoglobulin heavy chain and light chain involved. 

The Immunotyping, Serum is indicated when protein electrophoresis demonstrates a suspicious monoclonal band or when clinical features such as persistent bone pain, unexplained anemia, recurrent infections, hyperproteinemia, renal dysfunction, hypercalcemia, or elevated erythrocyte sedimentation rate (ESR) raise suspicion of an underlying plasma cell or lymphoproliferative disorder. Immunotyping plays a pivotal role in the diagnosis and classification of disorders such as multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), Waldenström macroglobulinemia, AL amyloidosis, light chain (Bence Jones) myeloma, and other plasma cell dyscrasias. It also supports disease classification, prognostication, treatment planning, assessment of therapeutic response, and long-term monitoring for disease progression or relapse.