IDH 1 & 2 (Isocitrate Dehydrogenase 1 & 2) gene mutation detection assay near me in Bangalore Rural

The IDH 1 & 2 (Isocitrate Dehydrogenase 1 & 2) gene mutation detection assay test is a genetic test that checks for specific changes (mutations) in the IDH1 and IDH2 genes, which are involved in important cell processes like metabolism and DNA regulation. Mutations in these genes can affect how cells function and may contribute to the development of cancer. Mutations in the IDH1 and IDH2 genes are commonly found in certain cancers, such as gliomas (including WHO grade II, III, and secondary grade IV glioblastomas), acute myeloid leukemia (AML), oligodendroglioma, chondrosarcoma, cholangiocarcinoma, and angioimmunoblastic T-cell lymphoma (AITL). These mutations usually affect specific positions in the gene (like IDH1 R132 or IDH2 R140/R172), leading to the buildup of a substance called 2-HG (D-2-hydroxyglutarate), which can cause changes in DNA and histone structure. The results of this test provide important information about genetic changes in the tumor, which can help guide further medical evaluation and treatment planning.

Note: One representative block of the tumor is required. However, 1-4 representative blocks of tumors are acceptable.

Disclaimer: In no event shall the liability of TATA 1MG exceed the amount of actual cost of test charges incurred by the customer as stated on the invoice issued by Tata 1mg.