EGFR Gene Analysis (Hot Spot) - 4 Exons (18 19 20 21) near me in Kalyan

EGFR gene analysis, specifically targeting the hot spots in exons 18, 19, 20, and 21, is a critical diagnostic tool in the realm of cancer research and treatment. Epidermal Growth Factor Receptor (EGFR) is a transmembrane receptor protein that plays a pivotal role in the growth and metastasis of tumors.

Patients with NSCLC harboring EGFR mutations are known to respond favorably to TKI therapy like Gefitinib and Erlotinib. However, the landscape of cancer treatment is complex, with some patients eventually developing resistance mutations, such as T790M and C797S, within the EGFR kinase domain, rendering them unresponsive to TKIs.

This sophisticated test employs ARMS real-time PCR technology to screen for 32 somatic mutations within exons 18, 19, 20, and 21 of the EGFR gene. It distinguishes between good responders, poor responders, and identifies the elusive resistance mutations, T790M and C797S, located in exon 20. Such precision in genetic analysis is invaluable in tailoring treatment strategies and improving patient outcomes in the fight against NSCLC.

Disclaimer: In no event shall the liability of TATA 1MG exceed the amount of actual cost of test charges incurred by the customer as stated on the invoice issued by Tata 1mg.