Celiac & IBD Panel, IgA by LIA near me in New Delhi

Celiac disease and inflammatory bowel disease (IBD) are chronic conditions that involve abnormal immune responses affecting the gastrointestinal tract. Celiac disease is a chronic, immune-mediated disorder of the small intestine triggered by the ingestion of gluten in genetically susceptible individuals. When people with celiac disease eat gluten—a protein found in wheat, barley, and rye—their immune system initiates an inflammatory response that damages the lining of the small intestine. IBD, including Crohn’s disease and ulcerative colitis, is characterized by persistent inflammation of the gastrointestinal tract. These diseases show symptoms, such as diarrhea, abdominal pain, weight loss, and fatigue. Antibody-based testing helps in differentiating between these conditions.

The Celiac & IBD Panel, IgA by LIA measures specific immunoglobulin A (IgA) antibodies that provide insights into gluten sensitivity and intestinal inflammation. Tissue Transglutaminase IgA (tTG IgA) and Deamidated Gliadin Peptide IgA (DGP IgA) are key blood tests for diagnosing celiac disease, detecting gluten-triggered immune activity and helping assess disease severity and response to a gluten-free diet. After starting a strict gluten-free diet, antibody levels gradually fall and may become undetectable within 1 to 12 months. Anti-Saccharomyces cerevisiae antibodies IgA (ASCA IgA) are immune antibodies directed against components (mannan/mannophosphopeptide) of baker’s yeast and are commonly found in patients with Crohn's disease, helping support its diagnosis.

This panel is recommended for individuals with chronic gastrointestinal symptoms such as persistent diarrhea, abdominal pain, bloating, unexplained weight loss, anemia, or malabsorption, especially when the clinical picture is unclear. It is also useful in people with a family history of celiac disease or IBD or in those with associated autoimmune conditions.

Fasting is not required for this test. Eat and drink as per the daily routine. However, a brief clinical history is preferred before sample collection. Additionally, let the doctor know about all the medications you are taking, as some can affect the test results. Continue eating foods containing gluten if testing for diagnosis, unless your doctor advises otherwise. 

Inform your doctor about all your medications, as some can affect the test results, potentially requiring dosage adjustments or temporary discontinuation. Always discuss your test results with your doctor, as ranges can vary by lab and individual health needs.