Celiac Disease Panel, IgA by LIA near me in Kanpur

Celiac disease is an autoimmune disorder in which ingestion of gluten triggers an abnormal immune response. Gluten is a protein found in common foods such as wheat, barley, and rye. The immune reaction against gluten damages the lining of the small intestine, leading to poor absorption of nutrients and a wide range of gastrointestinal and non-gastrointestinal symptoms. In children, the disease often leads to delayed growth, late-onset puberty, damaged tooth enamel, mood changes, and short height.

The Celiac Disease Panel, IgA by LIA measures specific IgA antibodies that are commonly elevated in individuals with celiac disease. These include tissue transglutaminase IgA (tTG IgA), which targets an enzyme involved in intestinal tissue repair, and deamidated gliadin peptide IgA (DGP IgA), which reacts to modified gluten peptides. The presence of these antibodies suggests an immune-mediated response to gluten and possible intestinal injury.

This test may be recommended if a person has symptoms such as chronic diarrhea, abdominal pain, bloating, unexplained weight loss, and fatigue. It is also useful in individuals with associated conditions such as type 1 diabetes, autoimmune thyroid disease, dermatitis herpetiformis, or a family history of celiac disease. The test can also be used to support diagnosis and monitor dietary compliance in individuals already diagnosed with celiac disease.

Fasting is not required for this test. Continue eating foods containing gluten if testing for diagnosis, unless your doctor advises otherwise.

Inform your doctor about all your medications, as some can affect the test results, potentially requiring dosage adjustments or temporary discontinuation. Always discuss your test results with your doctor, as ranges can vary by lab and individual health needs.