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Kidney Function Test

1200720
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NABL, ISO
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Overview
Interpretations
FAQ's
Tests Included
Kidney Function Test

Overview of Kidney Function Test

What is Kidney Function Test?

Kidneys play an important role in the removal of waste products and maintenance of water and electrolytes balance in the body. Kidney Function Test (KFT) includes a group of blood tests to determine how well the kidneys are working.

Sample Type

The sample type collected for Kidney Function Test is: Blood

Preparation for Kidney Function Test

  • Do not eat or drink anything other than water for 8-12 hours before the test.

Why Get Tested for Kidney Function Test?

The Kidney Function Test is performed:

·         As a part of routine health checkups

·         To help diagnose disease affecting the kidneys

·         To screen people at risk for the development of kidney diseases

·         To monitor treatment efficacy of kidney diseases





Understand more about Kidney Function Test

The kidneys are a pair of bean-shaped organs located on either side of the spinal column in the abdomen towards the back. The kidneys perform a number of important functions. The most important of these is that they filter the blood of waste products generated out of regular metabolic activities of the body, primarily urea, and excretes them out of the body through urine. They help in maintaining the normal pH and water balance of the body. The kidneys also play essential roles in the synthesis of Vitamin D and Red Blood Cells (RBCs).


The Kidney Function Test includes the following tests to monitor kidney function:


·        Blood Urea Nitrogen (BUN)/ Urea:

Blood Urea Nitrogen is a test to measure the amount of urea nitrogen present in the blood. Urea is a nitrogenous by-product of the metabolism of protein and its level in blood serves as an indication of the amount of nitrogen present in blood as urea. In simpler terms, BUN is the measure of the amount of nitrogen present in blood as urea. High BUN levels in the blood can be caused by kidney diseases, dehydration, and obstruction in the urinary tract due to kidney stones, prostate gland enlargement etc.

Urea test measures the level of Urea in blood. Urea is a final waste product formed from the breakdown of proteins. Urea is filtered out of the blood by the kidneys to excrete excess nitrogen present in blood through urine. Excess urea in blood is called uremia and can be caused by a number of conditions including kidney diseases.


·         Uric Acid:

This test measures the level of Uric acid in the blood. Uric acid is a waste product formed from the breakdown of purines, which are essential building blocks of DNA. It is also produced by the metabolism of proteinaceous food, especially red meat. Uric acid is excreted by the kidneys through urine and a small portion through stool. The uric acid test indicates the level of uric acid in the blood and serves as an indirect estimation of kidney function.

The excess uric acid in the blood is called hyperuricemia and causes gout due to the accumulation of uric acid crystals in the synovial fluid between joints. Hyperuricemia also causes the formation of hard lumps of uric acid crystals called tophi under the skin and at the top of the ears. Uric acid crystals can also accumulate in the kidneys and cause kidney stones.


·         Creatinine:

This test measures the level of Creatinine in blood. Creatinine is a waste product formed from the normal breakdown of muscles in the body. Creatinine is almost completely excreted by the kidneys, so their levels in blood serve as an indication of kidney function.

Excess creatinine in the blood can be found due to decreased elimination from the kidneys as well as due to increased creatinine production by muscular breakdown, eating cooked meat, protein supplements, etc.


·         BUN/Creatinine Ratio:

BUN/Creatinine Ratio compares the levels of nitrogen as urea in blood to the levels of creatinine in the blood. This ratio serves as a more accurate representation of kidney function. It is also used to check for dehydration since the BUN level increases in dehydration while creatinine levels remain the same. Low BUN to creatinine ratio can be caused by a low protein diet, liver cirrhosis, rhabdomyolysis (muscle disease), Syndrome of inappropriate antidiuretic hormone secretion (SIADH) as well as during pregnancy.


What Results of Kidney Function Test mean?

Interpretations

Normal levels:

·         Urea:

2.5-7.8 mmol/L


 ·        BUN:

7 to 20 mg/dL


·         Uric Acid:

Adult Female: 2.4 to 6.0 mg/dL

Adult Male: 3.4 to 7.0 mg/dL

Children: 3 to 4 mg/dL


·         Creatinine:

Adult males: 0.6 to 1.2 mg/dL

Adult females: 0.5 to 1.1 mg/dL


·         BUN/Creatinine Ratio:

          12:1 to 20:1


Increased levels of each of these parameters can indicate a number of conditions and not necessarily health disorders. For example, increased creatinine levels can occur due to heavy exercise, consumption of cooked meat, or taking protein supplements apart from kidney diseases. Thus, these parameters are interpreted in combination and further tests are performed to confirm health disorders.


Patient Concerns about Kidney Function Test

Frequently Asked Questions about Kidney Function Test

Q. How is this test performed?
This test is performed on a blood sample. A syringe with a fine needle attached is used to withdraw blood sample from a blood vessel in your arm generally from the inner side of the elbow area. The doctor, nurse or the phlebotomist will tie an elastic band around your arm which will help the blood vessels to swell with blood and hence makes it easier to withdraw blood. You may be asked to tightly clench your fist. Once the veins are clearly visible, the area is cleaned with an antiseptic solution and then the needle is inserted into the blood vessel to collect the sample. You may feel a tiny pinprick during the procedure. Blood sample once collected is then sent to the laboratory.
Q. Is there any risk associated with this test?
There is no risk associated with the test. However, as this test involves a needle prick to withdraw the blood sample, rarely, a patient may experience increased bleeding, hematoma (blood collection under the skin) formation, bruising or infection at the site of needle prick.
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Tests Included in Kidney Function Test(4 tests)

  • Urea/ Blood Urea Nitrogen
  • BUN/Creatinine Ratio
  • Uric Acid
  • Creatinine

Provided By

NABL

ISO

Sahyadri Speciality Labs is committed to provide the highest quality of Medical Laboratory services. There is a continual effort to ensure that the staff of the lab understands the Quality Policy & all the quality documentation, as well as follows the Quality manual and implements the Quality System Procedures all the time. By employing QMS, the lab strives to achieve the highest standard of service to provide the most reliable results, nearest to the true value and at most competitive rates. The lab is committed to good & ethical professional practices giving highest priority to client’s confidentiality and ensuring the reporting of the test values without any bias or influence. The lab implements the QMS so as to conform to ISO 15189:2007 and NABL 112 with the objective of Reducing reporting errors to the minimum, Minimizing customer complaints, Achieving maximum growth of the lab.
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