Overview of Dual Marker
What is Dual Marker?
Preparation for Dual Marker
- Please keep the hard copy of your latest pregnancy ultrasound report ready at the time of your test..
Why Get Tested for Dual Marker?
To detect Down’s syndrome
To detect Trisomy 18
Ladies having a family history of any of these syndromes
Understand more about Dual Marker
This test measures the levels of b-hCG and PAPP-A in blood with the ultrasound test. b-hCG is a hormone which is produced by the cells in the developing placenta during pregnancy. The levels of b-hCG increases in early pregnancy. The role of b-hCG in early pregnancy is to maintain the function of corpus luteum (the hormone-secreting structure that develops in an ovary). During the first three weeks production of b-hCG increases reaching to peak levels at 10th week (from the last menstrual cycle). After that, the levels of b-hCG start to fall to negligible within a few weeks after delivery.
PAPP-A is secreted by the placenta and its levels increase with duration of pregnancy. Variety of tissues express PAPP-A at very lower levels. Plaques which are not stable in coronary arteries also express PAPP-A in high levels.
What Results of Dual Marker mean?
All pregnant women should be screened for any pre-birth abnormalities irrespective of age. The ideal duration of this test is between 10 - 13 weeks of pregnancy. But it can be done between 9 - 13.6 weeks of pregnancy.
Patient Concerns about Dual Marker
Frequently Asked Questions about Dual Marker