What is Desmoglein I Antibody?
The Desmoglein I antibody test or DSG I antibody test is performed to screen for and diagnose Pemphigus. Pemphigus is an autoimmune disease where antibodies are produced against Desmoglein, which forms a type of glue that joins the epidermal cells or skin cells together. Antibodies target and destroy desmoglein, causing pemphigus.
Why is Desmoglein I Antibody done?
- To diagnose the causes of blisters or lesions on the skin surface and the mucosal membranes of the mouth and genitals
- To assess painful blisters that start near the mouth
- When crusting and peeling of skin at or near the blisters appears
- To diagnose pemphigus
Preparation for Desmoglein I Antibody
- No special preparation required
Sample Type for Desmoglein I Antibody
The sample type collected for Desmoglein I Antibody is: Blood