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Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
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Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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TORCH PANEL IgG EXTENDED

TORCH PANEL IgG EXTENDED Includes 5 testsView All
You need to provide
Blood
This test is for
Male, Female

Understanding TORCH PANEL IgG EXTENDED


What is TORCH PANEL IgG EXTENDED?

Perinatal infections account for 2-3% of all congenital anomalies. TORCH which includes Toxoplasma, Rubella, Cytomegalovirus & Herpes Simplex virus, are some of the most common infections associated with Congenital anomalies. Most of the TORCH infections cause mild maternal morbidity, but have serious fetal consequences. Demonstration of Toxoplasma IgG in the serum of person with eye lesion helps in diagnosing Ocular toxoplasmosis while persistent or increasing IgG antibody levels in the infant compared with the mother and/or positive result of Toxoplasma specific IgM or IgA are diagnostic of Congenital toxoplasmosis. Demonstration of rising antibody titer (four fold) in acute and convalescent sera taken 2-3 weeks apart are indicative of postnatal Rubella infection and to check response to Rubella vaccination. Single test results of CMV IgG are useful in screening organ transplant recipients and donors before transplantation and donors of blood products that are to be administered to premature infants and bone marrow transplant patients. Positive result of HSV (1/2) IgG indicates past infection with Herpes Simplex virus or administration of HSV immunoglobulins. This test differentiates between Herpes Type 1 & 2 infections.

What does TORCH PANEL IgG EXTENDED measure?

Contains 5 tests
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Toxoplasma gondii - IgG

A Toxoplasma gondii - IgG test measures the presence of immunoglobulin G (IgG) antibodies specific to the Toxoplasma gondii parasite in the blood. These antibodies indicate a previous (past) exposure to the parasite. The presence of IgG antibodies indicates that you have had an infection, but it does not tell when. A high avidity in the IgG avidity test strongly suggests the infection happened more than 4 months ago. However, a low avidity result alone cannot be used to diagnose when the infection occurred, and further clinical evaluation is needed.

In general, having IgG antibodies to Toxoplasma gondii suggests a certain level of protection, but the effectiveness and duration of this protection can depend on factors such as the individual’s overall health, the strain of the parasite, and other immune-related considerations. 

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Rubella Virus - IgG

The Rubella Virus - IgG test measures the presence of Immunoglobulin G (IgG) antibodies specific to the rubella virus in an individual's blood. IgG antibodies are indicative of previous exposure or vaccination against rubella. This test helps assess an individual’s immunity status to the virus. If the IgG antibodies are detected, it suggests that the individual has either been vaccinated against rubella or has had a previous infection, leading to the development of immune protection. 

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Herpes Simplex Virus 1 IgG

A Herpes Simplex Virus 1 IgG test determines the presence of IgG antibodies against HSV-1 in response to the Herpes infection. The body begins to make IgG antibodies around 18 to 21 days after the exposure of the virus and remains in the body for life. The presence of IgG antibodies generally indicates past exposure and immunity against herpes infection. Getting tested helps manage herpes infection and prevent it from spreading further as the HSV-1 remains dormant in the body after the initial infection and can reactivate at various times, leading to recurrent outbreaks.

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Cytomegalovirus IgG Antibody

A Cytomegalovirus IgG Antibody test measures the presence of IgG antibodies in the blood, indicating a previous CMV infection. IgG antibodies are produced several weeks after the initial CMV infection. IgG levels rise during the active infection, then stabilize as the CMV infection resolves and the virus becomes inactive. Once exposed to CMV, you will have some measurable amount of CMV IgG antibody in your blood for the rest of your life, which provides protection from getting another primary infection (immunity). However, if you have a weak immune system, the virus can reactivate and cause serious symptoms or organ damage.

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Herpes Simplex Virus 2 IgG

A Herpes Simplex Virus 2 IgG test looks for the presence of IgG antibodies against HSV-2  in response to the Herpes infection. IgG antibodies are the most frequent type of antibody, which are developed around 18 to 21 days after the virus invades the body and remains in the body for life. Thus, the presence of IgG antibodies typically means an individual has been infected with the HSV-2 at some point. Detection of HSV-2 infection allows doctors to provide necessary support and guidance to individuals suffering from genital herpes, leading to better treatment outcomes and improved quality of life.

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