Test Detail
Overview
Interpreting Results
FAQ's
Tests Included

Content created by

Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
Want to know more?
Read our Editorial Policy

Kidney Function Test with Electrolytes

(KFT)
ADD TO CART
KFT Test Includes 6 testsView All
Kidney Function Test with Electrolytes
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. Do not eat or drink anything other than water for 8-12 hours before the test.

Overview


What is KFT?

This test is done to evaluate the function of your kidneys or if you have symptoms that may indicate a kidney disorder like painful urination, blood in urine, frequent urges to urinate, high blood pressure, or swelling of hands and feet. This test also helps to analyze other conditions that can harm the kidneys like diabetes or high blood pressure.


Why is KFT done?

The Kidney Function Test with Electrolytes is performed:

  • As a part of routine health checkups

  • To assess problems in the water and pH balance of the body

  • To help diagnose any disease affecting the kidneys

  • To screen people at risk for the development of any kidney diseases

  • To monitor treatment efficacy of kidney diseases



What does KFT Measure?

This is a test panel done to evaluate the kidney functions. It contains a group of tests integrated to collectively analyze any malfunction related to the kidney.

The kidneys are a pair of bean-shaped organs located on either side of the spinal column in the abdomen towards the back. The kidneys perform a number of important functions. The most important of these is that they filter the blood and separate the waste products generated out of regular metabolic activities of the body, primarily urea. Following the separation, the kidneys excrete the waste products out of the body through urine. They help in maintaining the normal pH level and water balance of the body. The kidneys also play essential roles in the synthesis of Vitamin D and Red Blood Cells (RBCs).

The tests included in this panel analyze different substances which are required by our kidney such as minerals, proteins, electrolytes, etc. to function properly.

 

The Kidney Function Test includes the following tests to monitor kidney function:

·        Blood Urea Nitrogen (BUN)/ Urea:

Blood Urea Nitrogen is a test to measure the amount of urea nitrogen present in the blood. Urea is a nitrogenous by-product formed by the metabolism of protein, and its level in blood serves as an indication of the amount of nitrogen present in blood as urea. In simpler terms, BUN is the measure of the amount of nitrogen present in blood in the form of urea. High BUN levels in the blood can be caused as a result of kidney diseases, dehydration and obstruction in the urinary tract due to kidney stones, prostate gland enlargement, etc.

Urea test measures the level of urea in the blood. Urea is a final waste product formed from the breakdown of proteins. Urea is filtered out of the blood by the kidneys to excrete excess nitrogen present in the blood through urine. Excess of urea in blood is called uremia and can be caused by a number of conditions including kidney diseases.

·         Uric Acid:

This test measures the level of uric acid in the blood. Uric acid is a waste product formed from the breakdown of purines, which are essential building blocks of DNA. It is also produced by the metabolism of proteinaceous food, especially red meat. Uric acid is excreted from the body by the kidneys through urine and a small portion through stool. Although indirectly but uric acid test helps in estimating the proper functioning of the kidneys, .

The presence of excess amounts of uric acid in the blood is called hyperuricemia. This accumulation of uric acid crystals in the synovial fluid between joints lead to the formation of gouts. Hyperuricemia also causes the formation of hard lumps of uric acid crystals called tophi under the skin and at the top of the ears. Uric acid crystals can also accumulate in the kidneys and cause kidney stones.

·         Creatinine:

This test measures the level of Creatinine in blood. Creatinine is a waste product formed from the normal breakdown of muscles in the body. Creatinine is almost completely excreted by the kidneys, so their levels in the blood serve as an indication of improper kidney function.

The levels of creatinine in the blood can rise due to decreased elimination from the kidneys as well as due to increased creatinine production by muscular breakdown, eating cooked meat, protein supplements, etc.

·         BUN/Creatinine Ratio:

BUN/Creatinine Ratio compares the levels of nitrogen as urea in the blood to the levels of creatinine in the blood. This ratio serves as a more accurate representation of kidney function. An increase in the ratio can be seen in case of dehydration while creatinine levels remain the same. Low BUN to creatinine ratio can be caused due to a low protein diet, liver cirrhosis, rhabdomyolysis (muscle disease), syndrome of inappropriate antidiuretic hormone secretion (SIADH) as well as during pregnancy.


Electrolytes: The serum electrolyte test measures the following electrolytes:

  • Sodium (Na+)

  • Potassium (K+)

  • Chloride (Cl-)

Electrolytes play an important role in a number of body functions like metabolism, neuromuscular functioning, maintaining hydration, and pH (acid-base balance). Electrolytes also help in the entry of nutrients into the cells and removal of waste products from the cells. Electrolytes carry an electrical charge which can be either negative or positive and exist as dissolved salts in blood and body tissues. The Serum Electrolyte test measures the following important electrolytes:

Sodium (Na+)

Sodium is an essential body electrolyte which, along with potassium, chloride, bicarbonate, etc.helps to maintain the normal fluid and pH balance of the body. It is also vital for cellular metabolism, and in the activity of nerves and muscles and transmission of impulses between them. Sodium is present in all the body fluids. The highest concentration of sodium is found in blood and extracellular fluid.

Sodium is supplied to the body principally through dietary salt (sodium chloride or NaCl), and a small portion of sodium is absorbed through other food items. The required portion is absorbed by the body and the remaining is excreted by the kidneys through urine. The body maintains a very narrow range of sodium concentration by three mechanisms:

·         Secretion of hormones natriuretic peptides and aldosterone to control sodium elimination through urine

·         Secretion of antidiuretic hormone (ADH), also called Vasopressin, to control the volume of water eliminated through urine

·         Induction of thirst

Any disruption in the above-mentioned mechanisms gives rise to an imbalance in the concentration of sodium in the blood to produce Hyponatremia (low blood sodium concentration), or Hypernatremia (high blood sodium concentration). Both these conditions produce a number of symptoms and may even lead to death.

Potassium (K+)

Potassium is one of the essential body electrolytes along with sodium, chloride, bicarbonate, etc. As an electrolyte, potassium helps to regulate the amount of fluids present in the body and to maintain a correct pH balance. It performs a vital role in cellular metabolism and transport of nutrients and waste products in and out of cells. It is also essential in the transmission of nerve impulses to muscles and muscle activity.

Sufficient amount of potassium required by the body is absorbed from dietary sources, and the remaining unabsorbed potassium is excreted by the kidneys. The hormone called aldosterone maintains the body potassium level within a small normal range. Aldosterone acts on the nephrons present in the kidneys and activates a sodium-potassium pump which helps the body to reabsorb sodium and excrete potassium. This helps to maintain the potassium concentration in the blood within its normal range. Deviation of potassium concentration from its normal range gives rise to Hyperkalemia (high potassium level in blood), or Hypokalemia (low potassium level in blood). Both these conditions may produce a number of symptoms, and may even be fatal if not controlled.

Chloride (Cl-)

Chloride is an essential mineral which acts as an electrolyte similar to potassium, sodium, bicarbonate, etc. It helps to maintain the normal fluid and electrolyte balance in the body. It also acts as a buffer to help maintain the pH balance of the body. It also plays an essential role in metabolism by producing hydrochloric acid (HCl) in the stomach for digestion. The highest concentration of chloride is found in blood and extracellular fluid (fluid present outside the cells).

Most of the chloride is supplied to the body through dietary salt (sodium chloride or NaCl), and a small portion is absorbed through other food items. The required portion is absorbed by the body and the remaining is excreted by the kidneys through urine. The concentration of chloride in blood is maintained within a very narrow range by the body. Its increase or decrease is directly correlated with the sodium levels.

Interpreting KFT results


Interpretations

Normal levels:

·         Urea: 2.5-7.8 mmol/L

 ·        BUN: 7 to 20 mg/dL

·         Uric Acid:

Adult Female: 2.4 to 6.0 mg/dL

Adult Male: 3.4 to 7.0 mg/dL

Children: 3 to 4 mg/dL

·         Creatinine:

Adult males: 0.6 to 1.2 mg/dL

Adult females: 0.5 to 1.1 mg/dL

·         BUN/Creatinine Ratio:

          12:1 to 20:1

Sodium (Na+)

Normal range: 135 to 145 mmol/L

Hyponatremia: Below 135 mmol/L

Hypernatremia: Above 145 mmol/L

Sodium concentration in the body is maintained within a narrow normal range which lies between 135 mmol/L and 145 mmol/L.

Hyponatremia or low blood sodium indicates that sodium concentration lies below the normal range.

Hypernatremia or high blood sodium indicates that sodium concentration lies above the normal range.

Potassium (K+)

Normal range: 3.5 to 5.0mmol/L (136.5 to 195μg/ml approx.)

Hypokalemia: Below 3.5mmol/L (Less than 136.5μg/ml approx.)

Hyperkalemia: Above 5.0mmol/L (Above 195μg/ml approx.)

Potassium concentration in the body is maintained within a narrow normal range between 3.5mmol/L and 5.0mmol/L.

Hypokalemia or low blood potassium indicates that potassium concentration lies below the normal range.

Hyperkalemia or high blood potassium indicates that potassium concentration lies above the normal range.

Chloride (Cl-)

Normal reference range:

  • Adults: 98 to 106 mEq/L (milliequivalents per liter)

  • Children: 90 to 110 mEq/L

  • Newborn: 96 to 106 mEq/L

       

Higher than normal chloride level is called Hyperchloremia.

Lower than normal chloride level is called Hypochloremia.


Increased levels of each of these parameters can indicate a number of conditions and not necessarily health disorders. For example, increased creatinine levels can occur due to heavy exercise, consumption of cooked meat, or taking protein supplements apart from kidney diseases. Thus, these parameters are also considered while interpreting the tests. Further tests are performed to confirm any health disorders.

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about KFT


Frequently Asked Questions about Kidney Function Test with Electrolytes

Q. How is the blood sample taken?
The healthcare provider takes a blood sample from the arm. The site from where the blood is to be withdrawn is cleaned with a swab of rubbing alcohol. This is then followed by inserting a small needle which has a tube attached to it for collecting blood. Once the sufficient blood for analysis is withdrawn, the needle is removed. The site is then covered with a gauze pad.
Q. Is there any risk associated with the withdrawal of blood sample procedure?
As such there is no risk but in few cases, bruising, bleeding, and infection at the puncture site can be seen. In very few cases, there can be swelling of the vein after the blood is withdrawn.
Q. What are the common risk factors for the development of kidney diseases?
Common risk factors that may lead to development of kidney diseases include: · Diabetes · Hypertension (high blood pressure) · Heart and cardiovascular diseases · Family history of kidney diseases
Q. What is Chronic Kidney Disease (CKD)?
Chronic Kidney Disease (CKD) or Chronic Kidney Failure is a medical condition characterized by the steady and progressive loss of proper kidney functioning which leads to complete kidney failure if left untreated. The kidneys filter out metabolic wastes out of the blood for excretion, and their progressive loss of function due to CKD causes these wastes to build up in the body to toxic levels. This may turn fatal in end-stage kidney failure. CKD may be caused by conditions that affect kidney function, including: · Diabetes Type 1 and 2 · Hypertension (high blood pressure) · Glomerulonephritis (inflammation of the filtering units of the kidneys called glomeruli) · Interstitial nephritis (inflammation of the tubules of the kidneys) · Polycystic kidney disease (formation of cysts in the kidneys) · Urinary tract blockage due to kidney stones, prostate gland enlargement, or some cancers · Vesicoureteral reflux (backward flow of urine into the kidneys) · Pyelonephritis (general kidney infection) Symptoms of CKD are not easily apparent in the early stages. They build up in number and intensity as the disease worsens, usually only when significant damage has already occurred.
Q. What are the common symptoms of kidney disease?
Common signs and symptoms of kidney diseases include: · Swelling of the lower limbs, ankles, thighs · Puffiness around the face and eyes or in the wrists and stomach · Frothy or dark-colored urine · Blood in urine · Reduced urine volume · Burning sensation during urination · Change in frequency of urination · Pain in the mid-back region below the ribs at the location of the kidneys
+ more

Tests Included (6 tests)


  • Kidney Function Test(includes 3 tests)

    Urea

    Creatinine

    Uric Acid

  • Serum Electrolyte(includes 3 tests)

    Potassium

    Chloride

    Sodium


NABL

The Thyrovision laboratories is one of the fastest growing referral clinical laboratories in the region. It's vision is to work with scientific approach towards providing the society a meaningful solution of the diagnostic needs and innovate newer methods to fulfill the need of the hour in the diagnosis of human diseases.
Know More

Available at Other Labs


INDIA’S LARGEST HEALTHCARE PLATFORM

150M+
Visitors
25M+
Orders Delivered
1000+
Cities
Get the link to download App
Reliable

All products displayed on 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

Know More About 1mgdownArrow
Access medical and health information

1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1000 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.