Overview of Prostate Specific Antigen (Total) PSA
What is Prostate Specific Antigen (Total) PSA?
Why is Prostate Specific Antigen (Total) PSA done?
The PSA Test is performed:
· To screen for and help diagnose prostate cancer
· To detect and diagnose diseases of the prostate gland like BPH
· To monitor the effectiveness of treatment for prostate cancer
What does Prostate Specific Antigen (Total) PSA Measure?
The PSA Test measures the total PSA levels (both free and bound) in blood.
PSA is a protein which is secreted by the prostate gland. The prostate gland is a male accessory reproductive organ, the secretion of which contributes to the formation of the seminal fluid. Most of the PSA produced is secreted in the seminal fluid along with prostatic secretions and only a small amount is secreted into the bloodstream. PSA is considered to be a tumor marker since its levels in the blood are elevated in prostate cancer and BPH, and it is used as a preliminary screening test before further diagnostic procedures.
PSA in blood is found as either complexed PSA (bound to other proteins) or free PSA. The PSA Test usually calculates the total PSA levels in blood including both free and complexed forms. Separate tests for the levels of these two forms can be used to distinguish between prostate cancer and BPH.
Preparation for Prostate Specific Antigen (Total) PSA
- The sample should be collected before a digital rectal examination or rectal prostatic ultrasonography is performed and before or several days after the prostate biopsy.
Sample Type for Prostate Specific Antigen (Total) PSA
Interpreting Prostate Specific Antigen (Total) PSA results
The normal value of PSA in blood is below 4.0 ng/ml
PSA level roughly between 4.0 and 10.0 ng/ml is considered a “grey zone”.
Lower than 4.0 ng/ml PSA in blood indicates very low risk for prostate cancer or BPH, while higher than 10.0 ng/ml indicates a very high risk of developing prostate cancer or BPH.
Different forms of PSA testing, as well as other tests, are recommended for further diagnosis.
Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Prostate Specific Antigen (Total) PSA
Frequently Asked Questions about Prostate Specific Antigen (Total) PSA