Total Iron Binding Capacity

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Overview
Interpretations

Overview of Total Iron Binding Capacity

What is Total Iron Binding Capacity?

It may be ordered as a part of iron profile when your doctor suspects that you have either deficiency of iron or overload. Mostly, it is ordered when your CBC or peripheral smear shows that you have microcytic hypochromic anemia. Most common symptoms of anemia are fatigue, weakness, pale skin, headaches.

Sample Type

The sample type collected for Total Iron Binding Capacity is: Blood

Preparation for Total Iron Binding Capacity

  • Do not eat or drink anything other than water for 8-12 hours before the test.

Why Get Tested for Total Iron Binding Capacity?

  1. If you have signs or symptoms of iron deficiency anemia like pallor, fatigue, weakness, headaches
  2. If your CBC shows that your hemoglobin and hematocrit are low and RBC’s are smaller and paler than normal which usually suggest iron deficiency anemia 
  3. If you have signs or symptoms of increased accumolation of iron in the body like joint pain, abdominal pain, fatigue, loss of body hair


What Results of Total Iron Binding Capacity mean?

Interpretations

       The results of TIBC are usually read in conjunction with other iron tests. 

  • A high TIBC usually indicates iron deficiency anemia but can also be increased in pregnancy 
  • A low TIBC may be associated with hemochromatosis, sideroblastic anemia, liver disease, malnutrition 

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