Coombs Test - Indirect

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Overview
Interpretations

Overview of Coombs Test - Indirect

What is Coombs Test - Indirect?

The Indirect Coombs test is performed to screen for the presence of antibodies against Red Blood Cells (RBCs). If present, these antibodies will target and destroy foreign RBCs acquired through blood transfusions, or those present in the fetus by the antibodies of the mother.

Sample Type

The sample type collected for Coombs Test - Indirect is: Blood

Preparation for Coombs Test - Indirect

  • No special preparation required

Why Get Tested for Coombs Test - Indirect?

  1. To screen the recipient of a blood transfusion before the transfusion is done
  2. To screen the mother’s blood for antigens that can target the RBCs of the newborn
  3. To detect type of anemia
  4. For evaluation of hemolytic anemia

What Results of Coombs Test - Indirect mean?

Interpretations

Positive results for the Indirect Coombs test indicates that antibodies against one or more antigens being screened are present in the blood sample being tested. When tested positive in a pregnant woman, it indicates the presence of Rh antibody in the mother’s blood that may destroy the RBCs of the baby in some cases.

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NABL

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