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Hb HPLC (Hb Variants Estimation by HPLC) in Mohali
Also known as Hb Electrophoresis, Abnormal Hb studies, Hemoglobin variant analysis
You need to provide
Blood
This test is for
Male, Female
Test Preparation
Understanding Hb HPLC (Hb Variants Estimation by HPLC) in Mohali
What is Hb HPLC (Hb Variants Estimation by HPLC) in Mohali?
The Hb HPLC (Hb Variants Estimation by HPLC) test is a specialized test used to identify and quantify normal and abnormal forms of hemoglobin in the blood. It is available at an affordable price in Mohali with Tata 1mg Labs. Hemoglobin (Hb) is an iron-rich protein that carries oxygen to organs and tissues. The Hb HPLC (Hb Variants Estimation by HPLC) test helps identify hemoglobin variants, such as HbA, HbD, and HbF, crucial for diagnosing conditions marked by abnormal hemoglobin production like thalassemia and anemia. It is valuable for individuals undergoing treatments like transfusions in cases of unexplained anemia or familial blood disorder history, enabling doctors to assess treatment effectiveness.
Your doctor may suggest an Hb HPLC test when a blood disorder such as thalassemia or sickle cell disease is suspected. Fasting is not required for the Hb HPLC (Hb Variants Estimation by HPLC) test; you can eat and drink normally per your daily routine. Inform your doctor if you recently underwent a blood transfusion, which may impact the test results.
What does Hb HPLC (Hb Variants Estimation by HPLC) measure?
An Hb HPLC (Hb Variants Estimation by HPLC) test is used to identify and quantify different types of hemoglobin in the blood to diagnose and monitor specific blood disorders. Different types of hemoglobin are Adult type (HbA2), Fetal type (HbF), Hemoglobin S (HbS), Hemoglobin C (HbC), and Hemoglobin E (HbE), etc.
Normal types of hemoglobin include:
- Hemoglobin (Hgb) A: The most common type of hemoglobin in healthy adults
- Hemoglobin (Hgb) F: Fetal hemoglobin, which is found in unborn babies and newborns. HgbF is replaced by HgbA shortly after birth.
A deranged level of HgbA or HgbF might indicate certain types of anemia.
Abnormal types of hemoglobin include:
- Hemoglobin (Hgb) S: This type of hemoglobin is found in sickle cell anemia, an inherited disorder that causes the body to make stiff, sickle-shaped red blood cells. Sickle cells can get stuck in the blood vessels, causing severe pain, long-term infections, and other complications.
- Hemoglobin (Hgb) C: This type of hemoglobin is associated with hemolytic anemia that develops when your red blood cells are destroyed more easily than normal red blood cells or have a shorter life span than normal red blood cells.
- Hemoglobin (Hgb) E: This type of hemoglobin is mainly found in people of Southeast Asian descent and may be associated with mild anemia or no symptoms.
- Hemoglobin (Hgb) D: Hb D disease (HbDD) is characterized by mild hemolytic anemia and mild to moderate splenomegaly. Hb D Punjab occurs with the most significant prevalence in Gujarat and Sikhs of Punjab.
Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Hb HPLC (Hb Variants Estimation by HPLC) in Mohali
Frequently Asked Questions about Hb HPLC (Hb Variants Estimation by HPLC) in Mohali
Q. What happens during an Hb HPLC (Hb Variants Estimation by HPLC) test?
During the test, your phlebotomist will collect the blood sample in a vial/test tube. The test tube is then submitted to the labs for analysis. An electric current is passed through the blood sample, which helps to segregate different hemoglobin into separate bands. Your blood sample is finally compared to a normal hemoglobin sample to give accurate test results.
Q. How is an Hb HPLC (Hb Variants Estimation by HPLC) test performed?
A phlebotomist (a trained professional to perform blood draws) will clean your skin using an antiseptic alcohol cotton swab or wipe and take blood samples from your vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.
Q. Is there any risk associated with the Hb HPLC (Hb Variants Estimation by HPLC) test?
There are minimal risks associated with the Hb HPLC (Hb Variants Estimation by HPLC) test. You might experience slight pain or bruising at the spot where the needle was inserted. The risk of infection or excessive bleeding is very low.
Q. Does Tata 1mg Labs offer an Hb HPLC (Hb Variants Estimation by HPLC) test in Mohali?
Yes, Tata 1mg Labs offers an Hb HPLC (Hb Variants Estimation by HPLC) test in Mohali. The test is easy to book, is pocket-friendly, and comes with a comprehensible report.
Q. Is home sample collection facility available for an Hb HPLC (Hb Variants Estimation by HPLC) test in Mohali with Tata 1mg Labs?
Yes, home sample collection for an Hb HPLC (Hb Variants Estimation by HPLC) test is readily available in Mohali. Tata 1mg Labs allows you to choose a date and time that suits your schedule for sample collection.
Q. How can I schedule an Hb HPLC (Hb Variants Estimation by HPLC) test with Tata 1mg Labs in Mohali?
If you want to schedule an Hb HPLC (Hb Variants Estimation by HPLC) test with Tata 1mg Labs in Mohali, the procedure is fairly easy and hassle-free. Follow these steps to book a test: 1). Visit the Lab Tests section on the Tata 1mg website. 2). Add the test you want in the cart. 3). Pick a time and date slot according to your convenience; however, do consider the necessary prerequisites while scheduling a test. 4). You will receive a notification with all the details once the test is scheduled.
Q. What is the cost of an Hb HPLC (Hb Variants Estimation by HPLC) test at Tata 1mg Labs in Mohali?
Tata 1mg Labs is a pocket-friendly platform for booking lab tests in Mohali. An Hb HPLC (Hb Variants Estimation by HPLC) test is available at an affordable price of Rs. 929.
Q. How long does Tata 1mg Labs take to give the reports of an Hb HPLC (Hb Variants Estimation by HPLC) test in Mohali?
At Tata 1mg Labs, we understand the importance of timely results. We strive to provide fast turnaround times for test results, allowing you to get the information you need promptly. On average, we take 48 hours to provide the reports of an Hb HPLC (Hb Variants Estimation by HPLC) test in Mohali.
Q. How can I get my Hb HPLC (Hb Variants Estimation by HPLC) report from Tata 1mg?
The e-report of your Hb HPLC (Hb Variants Estimation by HPLC) can be found on the Tata 1mg app in downloadable PDF form. This allows you to access your test results at convenience and securely share them with your healthcare provider for further consultation and guidance regarding your overall health. You can also opt for a hard copy of the reports at a minimal price.
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References
- Wajcman H, Moradkhani K. Abnormal haemoglobins: detection & characterization. Indian J Med Res. 2011 Oct;134(4):538-46. PMID: 22089618; PMCID: PMC3237254. [Accessed 30 Oct. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237254/
- Kohne E. Hemoglobinopathies: clinical manifestations, diagnosis, and treatment. Dtsch Arztebl Int. 2011 Aug;108(31-32):532-40. [Accessed 30 Oct. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163784/
- Forget BG, Bunn HF. Classification of the disorders of hemoglobin. Cold Spring Harb Perspect Med. 2013 Feb 1;3(2):a011684. [Accessed 30 Oct. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552344/
- Khera R, Singh T, Khuana N, Gupta N, Dubey AP. HPLC in characterization of hemoglobin profile in thalassemia syndromes and hemoglobinopathies: a clinicohematological correlation. Indian J Hematol Blood Transfus. 2015 Mar;31(1):110-5. [Accessed 30 Oct. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275515/
- What is Thalassemia? [Internet]. CDC; 24 April 2023; [Accessed 30 Oct. 2023]. Available from: https://www.cdc.gov/ncbddd/thalassemia/facts.html
- What is Sickle Cell Disease? [Internet]. CDC; 06 July 6 2023; [Accessed 30 Oct. 2023]. Available from: https://www.cdc.gov/ncbddd/sicklecell/facts.html
- Billett HH. Hemoglobin and Hematocrit. In: Walker HK, Hall WD, Hurst JW, editors. Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd edition. Boston: Butterworths; 1990. Chapter 151. Available from: https://www.ncbi.nlm.nih.gov/books/NBK259/
- Ahmed MH, Ghatge MS, Safo MK. Hemoglobin: Structure, Function and Allostery. Subcell Biochem. 2020;94:345-382. [Accessed 30 Oct. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370311/
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