Test Detail
Overview
Interpreting Results
FAQ's

Content created by

Written by
Dr. Betina Chandolia
BDS, MDS - Oral Pathology and Microbiology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
Want to know more?
Read our Editorial Policy

CA125

CA125
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation required

Overview


What is CA125?

Cancer Antigen 125 (CA 125) is found in the majority of ovarian cancer cells. Thus, CA 125 is used as a tumor marker. This test measures the levels of CA 125 in the blood. It is done to monitor the treatment of ovarian cancer.

Why is CA125 done?

  • To detect ovarian cancer

  • To monitor the treatment of ovarian cancer

  • To detect recurrence of ovarian cancer

  • To detect lump (mass) in the pelvic area


What does CA125 Measure?

CA 125 is a protein which is present on the surface of the majority of ovarian cancer cells. Thus, women having ovarian cancer will show high levels of CA 125. This test is used to monitor the treatment and recurrence of ovarian cancer.

In women, ovarian cancer is one of the most common causes of cancer death. Very few cases of ovarian cancers are detected at an early stage because of their non-specific symptoms (not targeting any exact reason). By the time these ovarian cancers are detected, they spread to other parts of the body. Therefore, it is important for women to know family history and symptoms, and go for regular check-ups and pelvic examinations.

Interpreting CA125 results


Interpretations

CA125 < 35.00 U/mL

This reference range is irrespective of age

Reference range may vary from lab to lab*

High levels may be seen in:

  • Ovarian cancers

  • Pregnancy 

  • Menstruation

  • Ovarian cysts

  • Inflammatory diseases of Pelvis

  • Cirrhosis

  • Hepatitis

  • Endometriosis

  • Other tumors such as lung, colorectal, breast, or gastrointestinal tumors

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about CA125


Frequently Asked Questions about CA125

Q. Is there any preparation required before the test?
Inform the doctor about the medications you may be taking. No other specific preparations are usually required before this test.
Q. How is the blood sample taken?
The healthcare provider takes a blood sample from the arm. The site from where the blood is to be withdrawn is cleaned with a swab of rubbing alcohol. This is then followed by inserting a small needle which has a tube attached to it for collecting blood. Once the sufficient blood for analysis is withdrawn, the needle is removed. The site is then covered with a gauze pad.
Q. Is there any risk associated with the withdrawal of blood sample procedure?
As such there is no risk but in few cases, bruising, bleeding, and infection at the puncture site can be seen. In very few cases, there can be swelling of the vein after the blood is withdrawn.
Q. Are levels of CA125 seen high in all ovarian cancer?
No, in a few cases high levels of CA125 are not seen in ovarian cancer, CA125 is not present on all the ovarian cancer cells.
Q. Is Ca 125 a screening test for ovarian cancer?
No, CA 125 is not a screening test, as it does not show exact reason or symptoms. CA 125 is produced in small amounts in normal tissues and by other cancers as well.
Q. Are there any other non-cancerous conditions where high levels of CA125 can be seen?
Yes, other non-cancerous conditions such as pregnancy, menstruation, and inflammatory disease of the pelvis can show moderately high levels of CA125.
Q. What is pelvic inflammatory disease?
Pelvic inflammatory disease is an infection which includes the reproductive organs such as fallopian tubes, ovaries, cervix, and uterus. The symptoms include pain in abdomen, fever, pain while having sex, pain while passing urine, foul-smelling vaginal discharge, and irregular bleeding between periods.
+ more

NABL

ISO

CAP

Sterling Accuris Diagnostics is an ISO 9001:2015 Certified Company. It is the largest and most comprehensive pathology laboratory of Gujarat. At Sterling Accuris Diagnostics, we provide a wide range of pathology services that fit the needs of an individual. Moreover, we have the expert team of pathology specialists and the technologically advanced infrastructure to help meet individual needs.
Know More
User Reviews

P
Praful
Best
K
Kinnari Patel
Nice

Available at Other Labs



INDIA’S LARGEST HEALTHCARE PLATFORM

150M+
Visitors
25M+
Orders Delivered
1000+
Cities
Get the link to download App
+91
Reliable

All products displayed on 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Enjoy 20% off on allopathy medicines, up to 50% off on health products, up to 80% off on lab tests and free doctor consultations

India's only LegitScript and ISO/IEC 27001 certified online healthcare platform
Know More About 1mg
Access medical and health information

1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1000 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.