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Total Leucocyte Count (TLC)

White Blood Cell (WBC) count
Interpreting Results

Overview of TLC

What is TLC?

This test is ordered as a part of CBC, which may be performed when an individual undergoes a routine health examination. It is also commonly ordered when you have signs and symptoms of infection like fever, body aches, headache. Sometimes, it may be ordered when a particular therapy known to affect the WBC’s such as radiation or chemotherapy is started.

Why is TLC done?

  1. As a part of complete blood count or routine health check up 
  2. If you have signs or symptoms of infections or inflammation like fever, chills, body aches, headache 
  3. If your doctor is suspecting an autoimmune disorder 
  4. It is also ordered periodically to monitor the effectiveness of treatment after radiation therapy or chemotherapy

Preparation for TLC

  • No special preparation required

Sample Type for TLC

The sample type collected for Total Leucocyte Count is: Blood

Interpreting TLC results


  • High TLC also called leucocytosis may be seen in a large number of conditions like infections usually bacterial or viral, inflammatory disorders like rheumatoid arthritis, leukemia and conditions that result in tissue death like trauma, burns etc 
  • Low TLC also called leucopenia can be seen in vitamin B12 deficiency, bone marrow damage with drugs, radiation, disease of immune system like HIV

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