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Rapid Plasma Reagin (RPR/ VDRL)

Nontreponemal Test, Syphilis Serology

What is RPR/ VDRL?

If you have symptoms or signs of syphillis infection like chancre on genitals or throat If you are pregnant If you are being treated for another sexually transmitted disease like gonorrheaIf you have HIV infection If you have one or more partners who have tested positive for syphillis

Why is RPR/ VDRL done?

  1. A negative blood test means that you are most likely not suffering from syphillis infection. But, it only means that there is no evidence of disease at the time of the test. Antibodies may not appear several weeks after exposure to the bacteria. Therefore, repeat testing at a later date is advised. 
  2. A positive test means you are most likely suffering form syphillis. It shoold be followed by a specific treponemal (syphillis) antibody test like FTA-ABS. A positive resolt on the second method confirms the previous resolt and that you are infected with syphillis.

Preparation for RPR/ VDRL

  • No special preparation required

Sample Type for RPR/ VDRL

The sample type collected for Rapid Plasma Reagin is: Blood

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NABL

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