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Prolactin Test

440
4.5
NABL, CAP, ISO
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Overview
Interpretations
FAQ's
Prolactin Test

Overview of Prolactin Test

What is Prolactin Test?

The prolactin test is done to measure the levels of prolactin in the blood to check and monitor the associated disease condition. Prolactin is a hormone produced by the pituitary gland which is situated at the base of the brain. Prolactin is normally produced in both males and non-pregnant females in small amounts. The main function of this hormone is to stimulate milk production (lactation) after the childbirth, so, it is also known as the milk-producing hormone. The levels of prolactin hormone are generally high during pregnancy and after childbirth. But, high levels of prolactin can also be seen in many disease conditions in both men and women.

Sample Type

The sample type collected for Prolactin Test is: Blood

Preparation for Prolactin Test

  • Blood sample should be collected 4 hours after waking.

Why Get Tested for Prolactin Test?

  • To investigate the cause of abnormal breast milk discharge (galactorrhea), menstrual irregularities or infertility in non-pregnant women

  • To evaluate the role of prolactin in case of lactation failure in women after childbirth

  • To investigate the cause of erection problems, testicular failure or abnormal breast discharge in men

  • To investigate the cause of loss of sex drive (libido) in both men and women

  • To detect and monitor the progress of prolactinoma (tumor of the pituitary gland that causes high levels of prolactin) in both men and women


Understand more about Prolactin Test

The prolactin hormone is produced by the pituitary gland which is located at the base of the brain. The primary function of this hormone is to help in lactation i.e. production of milk after childbirth. Prolactin levels are usually high during pregnancy and after childbirth. During pregnancy, this hormone along with other hormones like estrogen and progesterone stimulates the breasts for milk production. After the childbirth, it helps to maintain the breast milk production. Suckling of the breasts by the baby is important for the release of prolactin hormone. If a woman stops breastfeeding, the level of prolactin hormone will return to normal.

Abnormally high levels of prolactin are seen in certain disease conditions like prolactinoma (non-cancerous tumor of the pituitary gland) in men and women. It is generally benign (non-cancerous) in nature and is seen more commonly in women. If the tumor is quite large, it can put pressure on the optic nerve and the patient may present with headache and visual disturbances.


What Results of Prolactin Test mean?

Interpretations

High levels of prolactin can be seen in:

  • Tumors of the pituitary gland that produces and release prolactin (Prolactinoma)

  • Diseases of the hypothalamus (a gland located in the brain)

  • Kidney disease

  • Liver disease

  • Hypothyroidism

  • Polycystic ovary disease (PCOD)

  • Conditions like anorexia nervosa (eating disorder)

Low levels of prolactin can be seen in:

  • Pseudohypoparathyroidism

  • Patients taking bromocriptine

  • Pituitary deficiency like necrosis or infarction of the pituitary gland


Patient Concerns about Prolactin Test

Frequently Asked Questions about Prolactin Test

Q. Are there any precautions required to be followed before the prolactin test?
The blood sample is collected 4 hours after waking up as the levels of Prolactin hormone are at the peak immediately after waking up. Inform your doctor if you are taking any medicines including herbals or any over the counter (OTC) medicines as they may interfere with your test values.
Q. Which medicines can affect the levels of Prolactin hormone?
Certain drugs can cause the low levels of Prolactin such as Dopamine (used in conditions like shock), Levodopa (used for Parkinson’s disease) or Ergot alkaloid derivatives (used for severe headaches). Certain drugs can cause elevated levels of Prolactin such as CNS depressants, Estrogen, drugs used for the treatment of hypertension like Reserpine, Verapamil, Methyldopa and drugs used for treating gastroesophageal reflux like cimetidine.
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Provided By

NABL

CAP

ISO

Established in 1995, Lifecare is the country's premier full-service diagnostic center with laboratory, providing expertise in imaging and digital pathology services. Our integrated diagnostic services help doctors personalize patient care to optimally treat disease and maintain health and wellness. We are committed to providing only the highest level of testing quality and service and working with you to provide unique solutions to your most challenging needs. A highly skilled team of medical professionals including physicians, scientists, medical technologists, medical technicians, lab assistants, biologists, chemists, microbiologists, geneticists, and other specialists work collaboratively. The department receives specimens for testing from patients and collection centers and is a reference laboratory for other clinics and hospitals both nationally and internationally. Lifecare's mission is to support the local delivery of laboratory services through the provision of exceptional reference laboratory services and by providing support services that facilitate and augment community integration efforts. We ensure Quality control programs that exceed industry guidelines for every patient sample. Proactive internal quality control team consisting of pathologists and laboratory personnel ensuring consistency and accuracy of specimen processing and diagnosis Our staff recognizes that specimens are patients, not just accession numbers in our lab. They are dedicated to combining the newest technologies, expertise, and quality in every sample they process.

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