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TriIodothyronine Free

250
4.8
NABL, CAP, ISO
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Overview
Interpreting Results
FAQ's
TriIodothyronine Free

Overview of FT3

What is FT3?

Triiodothyronine (T3) is a hormone secreted by the thyroid gland (small, butterfly-shaped gland located in front of the neck). The T3 hormone regulates the growth and metabolism of the body. T3 circulates in the blood in two forms: Free form (FT3) and Bound form. Free Triiodothyronine (T3) Test measures the Free form of the T3 hormone.

Why is FT3 done?

  • To diagnose thyroid diseases (Hypothyroidism or Hyperthyroidism)

  • To monitor the patient’s response to thyroid diseases’ treatment

  • To evaluate thyroid status in patients with altered distribution of thyroid binding proteins (e.g. pregnancy, dysalbuminemia)

What does FT3 Measure?

Free Triiodothyronine (T3) Test measures the levels of the Free form of the T3 hormone.
There is a feedback system in the body to maintain stable amounts of the thyroid hormones (T3 and T4) in the blood. When the levels of thyroid hormone decrease, the pituitary gland is stimulated to release TSH. This high TSH in turn leads to an increase in the release of thyroid hormones (T3 & T4) from the thyroid gland and vice-versa.

T3 hormone circulates in the blood in two forms:

1) Bound form - It is bound to proteins present in the blood which prevents it from entering body tissues.

2) Free form - It enters the body tissues where it is needed and thus is the active form.

The total T3 includes both the bound and the free forms circulating within the blood and can be affected by the amount of protein available in the blood to bind to them.

Majority of the T3 hormone is formed from T4 hormone and a smaller fraction is produced directly by the thyroid gland. Free Triiodothyronine (FT3) constitutes only 0.3% of the total T3 hormone. The two main proteins in blood that the T3 hormone binds itself  to are albumin and Thyroxine-binding globulin (TBG), also called Thyroid hormone Binding Globulin (THBG).

Hence, T3 hormone can be measured as Free T3 or Total T3. Free Triiodothyronine (T3) Test is also a part of Thyroid profile Free test which includes two more tests :

  • Thyroid Stimulating Hormone (TSH), and

  • Free Thyroxine (FT4).

The thyroid gland secretes the following hormones:

  • Triiodothyronine (T3)

  • Thyroxine (T4)

  • Calcitonin

Thyroid Stimulating Hormone (TSH), also called Thyrotropin is a hormone secreted into the blood by the Pituitary gland (a gland present in the brain).  It directs the thyroid gland to produce and release the thyroid hormones (T3 & T4) into your blood. The iodine absorbed from the food stimulates the thyroid glands to make the thyroid hormones.

The thyroid hormones are essential for growth and metabolism. If the thyroid gland produces very high amounts of T3 & T4 hormones, you may experience symptoms of weight loss, rapid heartbeat, tremors, sweating, anxiety, increased sensitivity towards heat, etc. and this is known as Hyperthyroidism.

The decreased production of thyroid hormones results in Hypothyroidism which may cause weight gain, fatigue, slow heart rate, increased sensitivity towards cold, depression, dry and thin hair, etc.

There is a feedback system in the body to maintain stable amounts of the thyroid hormones (T3 and T4) in the blood. When the levels of thyroid hormone decrease, the pituitary gland is stimulated to release TSH. This high TSH in turn leads to an increase in the release of thyroid hormones (T3 & T4) from the thyroid gland and vice-versa.

T3 hormone circulates in the blood in two forms:

1) Bound form - It is bound to the proteins present in the blood which prevents it from entering the body tissues.

2) Free form - It enters the body tissues where it is needed and thus is the active form.

The total T3 includes both the bound and the free forms circulating within  the blood and can be affected by the amount of protein available in the blood to bind to them.

Majority of the T3 hormone is formed from T4 hormone and a smaller fraction is produced directly by the thyroid gland. Free Triiodothyronine (FT3) constitutes of only 0.3% of the total T3 hormone. The two main proteins in the blood that the T3 hormone binds itself to are albumin and Thyroxine-binding globulin (TBG), also called Thyroid hormone Binding Globulin (THBG).

Hence, T3 hormone can be measured as Free T3 or Total T3. Free Triiodothyronine (T3) Test is also a part of Thyroid profile Free test which includes two more tests : Thyroid Stimulating Hormone (TSH) and Free Thyroxine (FT4).

Preparation for FT3

  • Do not eat or drink anything other than water for 8-12 hours before the test.

Sample Type for FT3

The sample type collected for TriIodothyronine Free is: Blood

Interpreting FT3 results

Interpretations

The results show either excessively high or low levels of free T3 in the blood samples. The normal range for free T3 is from 1.8 to 5.4 mcg/dl for men and women of all age groups.


Answers to Patient Concerns & Frequently Asked Questions (FAQs) about FT3

Frequently Asked Questions about TriIodothyronine Free

Q. What is Hyperthyroidism?
Hyperthyroidism is a condition in which the thyroid gland is overactive. This leads to an increased production of thyroid hormones by the thyroid gland. Causes of Hyperthyroidism include Graves’ disease, multinodular goiter, thyroid nodules, toxic adenoma, inflammation of the thyroid, overconsumption of iodine, and excess of synthetic thyroid hormone. Diagnosis of this condition can help relieve the symptoms and prevent long-term complications.
Q. What are the symptoms of Hyperthyroidism?
Symptoms of Hyperthyroidism include: Rapid heartbeat (tachycardia) — commonly more than 100 beats/minute — irregular heartbeat (arrhythmia) or pounding of your heart (palpitations), sudden weight loss, nervousness, anxiety, irritability, tremor (usually a fine trembling in your hands and fingers), changes in menstrual patterns, increased sensitivity towards heat, changes in bowel patterns (especially more frequent bowel movements), an enlarged thyroid gland (goiter) which may appear as a swelling at the base of your neck, increased appetite, sweating, fatigue, muscle weakness, sleep disturbances, skin thinning, fine and brittle hair.
Q. What is Hypothyroidism?
Hypothyroidism, also called underactive thyroid or low thyroid is a condition in which the thyroid gland does not produce enough thyroid hormones. It can be commonly caused by low intake of iodine in diet or Hashimoto's thyroiditis (an autoimmune disease). Other less common causes include previous treatment with radioactive iodine, injury to the pituitary gland which secretes TSH, intake of certain medicines, previous thyroid surgery or improper functioning of thyroid gland since birth.
Q. What are the symptoms of Hypothyroidism?
Symptoms of Hypothyroidism include: Tiredness (fatigue), constipation, feeling cold, dry skin, weight gain, muscle weakness, decreased sweating, depression, slower heart rate, increased blood cholesterol levels, pain and stiffness in your joints, impaired memory, problems of infertility or menstrual changes, muscle stiffness, aches, and tenderness, hoarseness, puffy face, dry and thin hair.
Q. How is this test performed?
This test is performed on a blood sample. A syringe with a fine needle is used to withdraw blood sample from a blood vessel in your arm generally from the inner side of the elbow area. The doctor, nurse or the phlebotomist will tie an elastic band around your arm which will help the blood vessels to swell with blood. This makes it easier to withdraw blood. You may be asked to tightly clench your fist. Once the veins are clearly visible, the area is cleaned with an antiseptic solution and then the needle is inserted into the blood vessel to collect the sample. You may feel a tiny pinprick during the procedure. Blood sample once collected is then sent to the laboratory.
Q. Is there any risk associated with this test?
There is no risk associated with the test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.
Q. How can hyperthyroidism affect a pregnant woman and her baby?
An untreated hyperthyroidism during pregnancy can lead to miscarriage, premature birth, low birth weight of the baby, preeclampsia (a very high rise in blood pressure in late pregnancy), thyroid storm (a sudden, severe worsening of symptoms of hyperthyroidism) and congestive heart failure.
Q. How can hypothyroidism affect a pregnant woman and her baby?
An untreated hypothyroidism during pregnancy can cause preeclampsia (a very high rise in blood pressure in late pregnancy), anemia, miscarriage, low birthweight, stillbirth (death or loss of a baby before or during delivery) and rarely, congestive heart failure. These problems are noticed mostly as a result of severe hypothyroidism. The mother’s thyroid hormones play an important role in the development of baby’s brain and nervous system, untreated hypothyroidism, especially during the first trimester can cause low IQ and other problems with normal development.
Q. What additional tests your doctor may order to detect the thyroid disease?
Your doctor may order the following tests: Thyroid stimulating hormone (TSH) test, T3 Total hormone test and Thyroid profile.
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CAP

ISO

We focus on providing patients quality diagnostic healthcare services in India. Through our network, we offer patients convenient locations for their diagnostic healthcare services and efficient service. With over 3368 diagnostic and related healthcare tests and services offered, we believe we are capable of performing substantially all of the diagnostic healthcare tests and services currently prescribed by physicians in India. Our key competitive strengths are: Business model focused on the patient as a customer and an established consumer healthcare brand associated with quality services, in a market where patients generally choose their diagnostic healthcare service provider. Well-positioned to leverage upon one of the fastest-growing segments of the Indian healthcare industry. A network whose growth yields greater economies of scale, combined with a hub and spoke model that is scalable for further growth. Centralized information technology platform that fully integrates our network and is scalable. Attractive financial performance, financial profile and return on invested capital. Experienced leadership team with strong industry expertise and successful track record. Some of our laboratories have achieved International Organization for Standardization, or ISO, certification for their quality systems. Our National Reference Laboratory has obtained ISO 9001:2008 certification (for the performance of routine and advanced diagnostic pathology testing services, including clinical trials), ISO 15189:2007 (for quality management in medical laboratories), ISO 15189:2012 certification (in the field of medical testing) and ISO 27001:2013 certification (for establishing an effective information management system that maintains and processes information security at our data center).

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