Test Detail
Interpreting Results

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Written by
Dr. Betina Chandolia
BDS, MDS - Oral Pathology and Microbiology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Creatinine - Spot

Creatinine - Spot
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This test is for
Male, Female
Test Preparation
  1. No special preparation required


What is Creatinine - Spot?

Creatinine spot test, also known as urine creatinine test. It measures the amount of creatinine in the urine. This test is advised to evaluate the health of your kidneys, to help diagnose kidney diseases, and to monitor treatment for kidney diseases. Creatinine is a waste product which is produced by muscles as a result of breakdown of the compound known as creatine. 

Why is Creatinine - Spot done?

The creatinine - spot test is done:

    • In case of signs or symptoms of kidney disease or damage

    • To evaluate normal functioning of kidneys

    • To diagnose kidney diseases

    • To monitor treatment for kidney diseases

    • As a part of comprehensive or metabolic panel

What does Creatinine - Spot Measure?

The creatinine - spot test measures the levels of creatinine in the urine. Creatinine is a waste product that is produced by the muscles due to the breakdown of a compound called Creatine. Creatinine is produced during the cycle of energy production which is required to contract muscles. Kidneys remove creatinine from the body by filtering it from the blood and then releasing it into the urine.

The body produces creatine and creatinine at a relatively same rate. Since kidneys filter most of the creatinine from the blood and release it into the urine, the blood levels can be used as an indicator to know how well the kidneys are functioning. The amount of creatinine produced depends on the muscle mass and general physique (size) of an individual. That is why levels of creatinine are higher in men as compared to women and children. 

Interpreting Creatinine - Spot results


The range of creatinine - spot urine test lies in between 24.00 mg/dL and 392.00 mg/dL*.

*Reference range may vary from lab to lab.

High levels

  • Damage to the blood vessels of the kidneys

  • Swelling of the blood vessels of the kidneys

  • Infection of the kidneys such as bacterial infections

  • Death of cells in small tubes of kidneys 

  • Prostate disease 

  • Kidney disease

  • Obstruction in the urinary tract

  • Reduced flow of blood to kidneys

Low levels of creatinine do not have any significance. The cause of low levels can be due to decreased muscle mass. 

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Creatinine - Spot

Frequently Asked Questions about Creatinine - Spot

Q. Is there any effect of exercise on creatinine levels?
No, the creatinine levels are not affected by moderate exercise. However, the levels may increase if the muscle mass is increased.
Q. What are the conditions in which high levels of creatinine are seen?
High levels of creatinine are seen in cases of kidney infections, damage to blood vessels of the kidneys, swelling of blood vessels of the kidneys, and death of cells in small tubes of kidneys. These increased levels can also be the result of prostate disease, kidney disease, obstruction in the urinary tract, reduced blood flow to the kidneys, and muscle injury. Moreover, some medicines can also cause levels of creatinine to rise.
Q. What are the conditions in which low levels of creatinine are seen?
Low levels of creatinine can be seen in cases of pregnancy.
Q. How is the urine sample collected?
As the test is performed on the urine sample. It is essential to prevent contamination of the sample with microorganisms naturally present on the skin. During urine collection, women should spread the labia (outer lips of the vagina) while men should retract or pull back the foreskin (fold of skin covering the glans or head of the penis). Start urinating normally and let some urine flow before collecting 20 to 30 ml urine the sterilized container available from the lab or any pharmacy. After collecting the sample, finish urinating into the toilet or urinal. This process is called midstream clean catch method. The urine sample may also be collected using a catheter inserted through the urethra directly into the urinary bladder. Sample collected through a catheter usually has no contamination.
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