locator iconlocator icon
All Labs
 
add to cart

Thyroxine Binding Globulin

5490
4.8
NABL, CAP, ISO
ADD TO CART
Overview
Interpreting Results
FAQ's
Thyroxine Binding Globulin

Overview of TBG

What is TBG?

T3 (Triiodothyronine) and T4 (Thyroxine) hormones are produced by the thyroid gland which binds with the proteins produced by the body. However, small amounts of T3 and T4 remains ‘free’ as it does not bind with the proteins. The protein bound T3 and T4 binds to Thyroxine Binding Globulin (TBG). TBG test is done to assess the thyroid tissues. It helps in the diagnosis of other thyroid disorders such as hypothyroidism and hyperthyroidism.This test measures the levels of TBG which helps in assessing thyroid problems.

Why is TBG done?

  • To diagnose hypothyroidism (low levels of thyroid)

  • To diagnose hyperthyroidism (high levels of thyroid)

  • To monitor treatment in patients with thyroid disease


What does TBG Measure?

Thyroxine Binding Globulin (TBG) test measures the levels of TBG which helps in assessing thyroid problems.
TBG is a serum binding protein which has a high affinity to bind to T3 and T4. In the routine, the thyroid gland maintains the level of free hormone i.e. which is not bound to the TBG. This test is done to assess the thyroid tissues. It helps in diagnosing thyroid disorders such as hypothyroidism and hyperthyroidism. The rise in levels is associated with the intake of oral contraceptives or estrogen therapy. Elevated levels of TBG can be seen during pregnancy or if a person has a family history. The decrease in TBG levels is associated with the intake of androgenic steroids, heavy doses of glucocorticoids, liver disease, nephrotic syndrome, congenital TGB variants and hypoproteinemic states


 

Preparation for TBG

  • No special preparation required

Sample Type for TBG

The sample type collected for Thyroxine Binding Globulin is: Blood

Interpreting TBG results

Interpretations

High levels may indicate:

  • Liver disease

  • Acute intermittent porphyria

  • Hypothyroidism


Low levels may indicate:

  • Acromegaly

  • Acute illness

  • Hyperthyroidism

  • Malnutrition

  • Nephrotic Syndrome


Answers to Patient Concerns & Frequently Asked Questions (FAQs) about TBG

Frequently Asked Questions about Thyroxine Binding Globulin

Q. What is Hyperthyroidism?
Hyperthyroidism is a condition in which the thyroid gland is overactive which leads to an increased production of thyroid hormones. Causes of hyperthyroidism include Graves’ disease, multinodular goiter, thyroid nodules, toxic adenoma, inflammation of the thyroid gland, overconsumption of iodine, and excess of synthetic thyroid hormone. Diagnosis of this condition can help relieve the symptoms and prevent long-term complications.
Q. What is Hypothyroidism?
Hypothyroidism, also known as underactive thyroid or low thyroid is a condition in which the thyroid gland does not produce enough thyroid hormones. It can be caused due to low levels of iodine intake in the diet or Hashimoto's thyroiditis (an autoimmune disease). Other less common causes that lead to hypothyroidism include previous treatment with radioactive iodine, injury to the pituitary gland, as a side-effect of certain medicines, previous thyroid surgery or improper functioning of thyroid gland since birth.
Q. How is this test performed?
This test is performed on a blood sample. A syringe with a fine needle is used to withdraw blood sample from a blood vessel in your arm, generally from the inner side of the elbow area. The doctor, nurse or the phlebotomist will tie an elastic band around your arm which will help the blood vessels to swell with blood. This makes it easier to withdraw blood. You may be asked to tightly clench your fist. Once the veins are clearly visible, the area is cleaned with an antiseptic solution. The needle is then inserted into the blood vessel to collect the sample. You may feel a tiny pinprick during the procedure. Blood sample, once collected, is then sent to the laboratory.
Q. Is there any risk associated with this test?
There is no risk associated with the test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.
Q. What additional tests can be performed in case the TBG results are not in the normal range?
If the TBG test results are not in the normal range, your doctor may ask for the following tests: Thyroid profile Free Anti Thyroperoxidase Antibody
Q. Can medicines have any effect on the levels of TBG test?
Yes, certain medicines such as prednisone, phenothiazines, dilantin, depakene, depakote, drugs such as opioids and opiates or hormonal therapy such as estrogen therapy can affect the levels of TBG.
+ more

Provided By

NABL

CAP

ISO

About Dr. Lal Pathlab

We focus on providing patients quality diagnostic healthcare services in India. Through our network, we offer patients convenient locations for their diagnostic healthcare services and efficient service. With over 3368 diagnostic and related healthcare tests and services offered, we believe we are capable of performing substantially all of the diagnostic healthcare tests and services currently prescribed by physicians in India. Our key competitive strengths are: Business model focused on the patient as a customer and an established consumer healthcare brand associated with quality services, in a market where patients generally choose their diagnostic healthcare service provider. Well-positioned to leverage upon one of the fastest-growing segments of the Indian healthcare industry. A network whose growth yields greater economies of scale, combined with a hub and spoke model that is scalable for further growth. Centralized information technology platform that fully integrates our network and is scalable. Attractive financial performance, financial profile and return on invested capital. Experienced leadership team with strong industry expertise and successful track record. Some of our laboratories have achieved International Organization for Standardization, or ISO, certification for their quality systems. Our National Reference Laboratory has obtained ISO 9001:2008 certification (for the performance of routine and advanced diagnostic pathology testing services, including clinical trials), ISO 15189:2007 (for quality management in medical laboratories), ISO 15189:2012 certification (in the field of medical testing) and ISO 27001:2013 certification (for establishing an effective information management system that maintains and processes information security at our data center).

Available at Other Labs