Carbamazepine

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3.8
NABL, CAP, ISO
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Overview
Interpretations
FAQ's
Carbamazepine

Overview of Carbamazepine

What is Carbamazepine?

Carbamazepine is a drug which is used in the treatment of seizures as in epilepsy (fits), mania, bipolar disorder, and some types of nerve pain. It is also used to reduce symptoms of alcohol withdrawal. The Carbamazepine Test is performed to measure the levels of carbamazepine in blood.

Sample Type

The sample type collected for Carbamazepine is: Blood

Preparation for Carbamazepine

  • No special preparation required

Why Get Tested for Carbamazepine?

The Carbamazepine Test is performed:

·         To establish the therapeutic dosage for carbamazepine in blood

·         To monitor carbamazepine levels at regular intervals to maintain therapeutic concentration after starting treatment

·         To check for carbamazepine toxicity if symptoms appear




Understand more about Carbamazepine

Carbamazepine is an anticonvulsant or anti-epileptic drug and is used mainly for the treatment of epileptic seizures (including partial seizures, generalized tonic-clonic seizures, and mixed seizures). The drug is also used to treat mood swings during bipolar disorder, especially mania, alcohol withdrawal symptoms, and cases of peripheral neuropathy during diabetes. It may be prescribed in combination with other medications.

Carbamazepine taken orally is absorbed in the intestinal tract and goes into the blood. In blood, most of it gets bound to plasma proteins like albumin and only a small portion remains free. Only the free carbamazepine remains metabolically active and the carbamazepine-protein complex remains inactive.

Carbamazepine levels are affected by a number of factors including liver function, the differential rate of absorption through the gastrointestinal tract, other drugs, levels of plasma proteins that form complex with it, and even the metabolized product of the drug itself. Since carbamazepine levels need to be maintained within a very narrow therapeutic range in blood, they are monitored continuously during treatment.


What Results of Carbamazepine mean?

Interpretations

Therapeutic Range: 4 to 12 µg/ml  (17 to 51 mmol/L)

The therapeutic range of carbamazepine may vary from person to person and due to a number of other factors. Hence, the therapeutic range is established for the patient at the beginning of treatment.

Lower carbamazepine concentration than the therapeutic range makes the drug ineffective in treatment.

Higher carbamazepine concentration than the therapeutic range induces symptoms associated with carbamazepine toxicity.


Patient Concerns about Carbamazepine

Frequently Asked Questions about Carbamazepine

Q. How is this test performed?
This test is performed on a blood sample. A syringe with a fine needle attached is used to withdraw blood sample from a blood vessel in your arm generally from the inner side of the elbow area. The doctor, nurse or the phlebotomist will tie an elastic band around your arm which will help the blood vessels to swell with blood and hence makes it easier to withdraw blood. You may be asked to tightly clench your fist. Once the veins are clearly visible, the area is cleaned with an antiseptic solution and then the needle is inserted into the blood vessel to collect the sample. You may feel a tiny pinprick during the procedure. Blood sample once collected is then sent to the laboratory.
Q. Is there any risk associated with this test?
There is no risk associated with the test. However, as this test involves a needle prick to withdraw the blood sample, rarely, a patient may experience increased bleeding, hematoma (blood collection under the skin) formation, bruising or infection at the site of needle prick.
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Thyrocare Technologies Limited is India's first and most advanced Totally Automated Laboratory having its strong presence in more than 2000 cities / towns in India and internationally. Thyrocare is India's first fully automated diagnostic laboratory with a focus on providing quality at affordable costs to laboratories and hospitals in India and other countries. Thyrocare operates with a Centralized Processing Laboratory (CPL) in Mumbai - India for esoteric tests; and Regional Processing Laboratory in major metro cities of India and other parts of Asia. We have focus on strong technologies, strong brands and strong systems that enable all laboratories to give their clients the best of science and technology at an affordable cost. With a belief that 'Quality' is the heart of any intelligent management, Thyrocare became one of the first Indian diagnostic laboratories to obtain internationally renowned quality accreditations like ISO 9001-2000 rating as early as 2001, which is now escalated to ISO 9001:2008; NABL (National Accreditation Board for Testing and Calibration Laboratories) in 2005 and CAP (College of American Pathologists) certification in 2007.
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