Microalbumin Creatinine Ratio, Urine
What is Microalbumin Creatinine Ratio, Urine?
Microalbumin Creatinine Ratio, Urine test is used to measure the amount of albumin in urine. Albumin level keeps fluctuating throughout the day, hence this test helps to measure the albumin level more accurately, as it gives a ratio of albumin to creatinine. Albumin is a protein found in the blood and is filtered by the kidneys. It is excreted in the urine in very low amount. The presence of high level of albumin in the urine is usually an indication of a kidney disease. This test is crucial as it helps to detect a kidney problem at an early stage even before the onset of any symptoms.
Values above normal indicate albuminuria. Sometimes a very low amount of albumin can also be due to urinary tract infection.
This test is recommended on a regular basis to the patients suffering from diabetes and hypertension as they are more prone to kidney problems.
Why is Microalbumin Creatinine Ratio, Urine done?
The microalbumin/creatinine ratio is done:
To detect early kidney disease in patients with diabetes or other risk factors, such as high blood pressure (hypertension)
As routine health checkup for patients of hypertension and type 1 or 2 diabetes
What does Microalbumin Creatinine Ratio, Urine Measure?
Usually, albumin and creatinine tests are done randomly (not timed) on a urine sample, and the results are used to calculate an albumin/creatinine ratio (ACR). This test gives a more accurate indication of how much albumin is being released into the urine.
The healthy kidneys keep healthy components such as albumin and filter waste from the blood. In case of kidney damage, albumin can leak through the kidneys and exit the body through urine.
In case of any damage caused to the kidney, albumin is one of the first proteins to leak through the kidney. This test is recommended in those patients who are at increased risk of kidney disease or damage such as patients with type 1 diabetes, type 2 diabetes, or high blood pressure.
Creatinine is a byproduct of muscle metabolism. Normally, it is released into the urine at a constant rate. The level of creatinine in the urine is an indication of the urine concentration. Thus, creatinine measurement can be used to indicate correct urine concentration when measuring albumin in a random urine sample.
The presence of a small amount of albumin in the urine can be an early indicator of kidney disease. The term ‘microalbuminuria’ is referred to a condition in which a small amount of albumin is present in the urine, while the term ‘albuminuria’ refers to a condition where there is presence of any amount of rise in albumin levels in the urine.
Interpreting Microalbumin Creatinine Ratio, Urine results
Creatinine value in mg/dl
The results are interpreted as microalbumin:creatinine ratio in mg/g
Reference range in mg/g creatinine
Normal / Non-diabetic
30 - 300
Reference range may vary from lab to lab*
Three samples should be collected within 3-6 months, from which at least two should be abnormal to consider for diagnosis.
Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Microalbumin Creatinine Ratio, Urine
Frequently Asked Questions about Microalbumin Creatinine Ratio, Urine