Test Detail

Content created by

Written by
Dr. Betina Chandolia
BDS, MDS - Oral Pathology and Microbiology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Acetyl Choline Receptor Antibody

(AchR Ab, ARAb)
You need to provide
This test is for
Male, Female
Test Preparation
  1. No special preparation required
  2. It is recommended that patient discontinues muscle relaxants and anesthetics for 24 hrs. prior to sampling as these drugs may affect test results.


What is AchR Ab, ARAb?

Acetylcholine Receptor Antibody or antibodies to the acetylcholine receptor (AChR), are used to identify myasthenia gravis (MG) and differentiate it from other illnesses that induce common characteristics, such as chronic muscle exhaustion and weakening.

When a thymoma is discovered during an imaging scan, the healthcare professionals may suggest an AChR antibody test. AChR antibodies are not commonly seen in the bloodstream. They are autoantibodies that signal an autoimmune reaction. Usually, the circulation contains no acetylcholine receptor antibodies (or less than 0.05 nmol/L). A negative test result does not eliminate the possibility of MG. AChR antibodies will be negative in up to 50% of patients with ocular MG (influencing only eye-related tissues) and about 10-15% of those with generalized MG. An abnormal result indicates that you have acetylcholine receptor antibodies in the blood.


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