Anti Centromere Antibodies
What is Anti Centromere Antibodies?
The Anticentromere Antibody test is a blood serum test performed to determine if anticentromere antibodies are present in blood and to diagnose systemic sclerosis.
Why is Anti Centromere Antibodies done?
The Anticentromere Antibody test is performed in case symptoms associated with CREST syndrome appears and a positive result is obtained in an Antinuclear Antibody test. CREST symptoms include:
• Calcinosis: Calcium deposits under skin
• Raynaud phenomenon: Episodes of reduced flow of blood to the fingers and toes, which causes them to turn white or blue
• Esophageal dysfunction: Swallowing difficulty, heartburn, and acid reflux
• Sclerodactyly: thick, tight, and shiny skin on hands and fingers
• Telangiectasia: Swollen capillaries and appearance of red spots on skin
Interpreting Anti Centromere Antibodies results
Presence of anti centromere antibodies in blood indicates the presence of Limited Cutaneous Scleroderma.