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Progesterone

520312
40% Coupon
3.1
ISO, NABH
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Overview
Interpreting Results
FAQ's
Progesterone

Overview of Progesterone

What is Progesterone?

Progesterone is a steroid hormone which, along with other female hormones, helps to prepare the female body for pregnancy and maintains a proper menstrual cycle. The Progesterone Test is performed to measure the levels of progesterone in blood.

Why is Progesterone done?

  • To identify the cause of female infertility by helping track ovulation (release of egg from ovary)
  • To help diagnose an ectopic pregnancy (a condition where the fertilized egg is implanted somewhere other than the uterus)
  • To monitor the treatment with progesterone hormone
  • To monitor the health of the fetus and placenta, especially in high risk pregnancy
  • To determine the cause of abnormal bleeding from the uterus

 



What does Progesterone Measure?

The progesterone test measures the levels of progesterone in the blood. Progesterone is a hormone which helps to prepare the female body for pregnancy and maintain normal menstrual cycle and coordinate  with other female hormones. Every month, the menstrual cycle begins with an increase in the level of estrogen hormone. This causes thickening of the inner lining of the uterus called endometrium. This coincides with an increase in levels of luteinizing hormone which induces the release of an egg from the ovary. Subsequently, a structure called corpus luteum forms on the ovary at the site where the egg was released. The corpus luteum produces progesterone hormone which arrests the endometrial growth and prepares the uterus for implantation of the fertilized egg.

At this juncture one of two things may happen. If the egg remains unfertilized, the corpus luteum slowly breaks down and progesterone levels fall. This induces breakdown of the endometrial lining and menstrual bleeding starts. However, if the egg is fertilized and attaches to the endometrium, the corpus luteum does not degenerate and continues progesterone secretion, thereby maintaining the thickened endometrial lining. After a few weeks of pregnancy, the placenta becomes fully formed and takes over the function of progesterone secretion till the completion of pregnancy. Therefore, increased progesterone levels are seen in pregnancy.

Levels of progesterone also fluctuates during normal menstrual cycle. Progesterone is secreted in much lower amounts in males, and is considered to play a small role in sperm development.

Few cancers can also result in abnormal progesterone levels in men and women.


Preparation for Progesterone

  • No special preparation required

Sample Type for Progesterone

The sample type collected for Progesterone is: Blood

Interpreting Progesterone results

Interpretations

If the result of a single progesterone test falls outside the normal range, it cannot be considered an abnormal result since progesterone levels change continuously. Abnormal results appear if the patient’s blood progesterone levels fall outside the normal range in multiple subsequent tests.

Apart from pregnancy, higher than normal progesterone levels can be seen in cases of:

·         Ovarian cysts

·         Ovarian cancer

·         Molar pregnancy or non-viable pregnancy

·         Congenital Adrenal Hyperplasia (CAH)

·         Adrenal cancer

Lower than normal progesterone levels can be seen in cases of:

·         Amenorrhea or no menstruation

·         Anovulation

·         Ectopic pregnancy

·         Miscarriage or death of fetus


Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Progesterone

Frequently Asked Questions about Progesterone

Q. How is this test performed?
This test is performed on a blood sample. A syringe with a fine needle is used to withdraw blood sample from a blood vessel in your arm, generally from the inner side of the elbow area. The doctor, nurse or the phlebotomist will tie an elastic band around your arm which will help the blood vessels to swell with blood. This makes it easier to withdraw blood. You may be asked to tightly clench your fist. Once the veins are clearly visible, the area is cleaned with an antiseptic solution. The needle is then inserted into the blood vessel to collect the sample. You may feel a tiny pinprick during the procedure. Blood sample, once collected, is then sent to the laboratory.
Q. Is there any risk associated with this test?
There is no risk associated with the test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.
Q. Is there any preparation required before the test?
Inform the doctor about the medications you may be taking. No other specific preparations are usually required before this test.
Q. What factors can affect the progesterone test results?
The factors which can affect the progesterone test results are: · Certain medications like steroids, birth control pills, ampicillin, clomiphene etc. · Recent exposure to radioactive substances, as in the case of undergoing imaging scans like Thyroid Scan or Bone scan · Time of day as progesterone levels fluctuate during day · Phase of menstrual cycle
Q. What other tests can be prescribed by your doctor in case of abnormal progesterone result?
Additional tests that may be prescribed in case of abnormal progesterone test result are: · Estrogen Test · hCG (Human Chorionic Gonadotropin) Test · Luteinising Hormone (LH) Test · Follicle Stimulating Hormone (FSH) Test · Uterine Ultrasound
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About DNA XPERTS

The PNDT registered Genetic Laboratory & Genetic Counselling center at DNA Xperts is the first of its kind center in East Delhi to offer Genetic Testing & Genetic Counselling services. Genetic counseling is the process of determining the risk you have of passing on an inheritable genetic disease to your baby and hence is advised before or during pregnancy for couples.

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